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White Spot Lesion clinical trials

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NCT ID: NCT05989750 Recruiting - White Spot Lesion Clinical Trials

Air-polishing With Erythritol During Orthodontic Tretament

AirPort
Start date: September 11, 2023
Phase: N/A
Study type: Interventional

Patients with multi-bracketed fixed orthodontic treatment are at increased risk of developing white spot lesions (WSL) and gingivitis. Various preventive strategies have been examined to prevent the development of WSLs. During initial non-surgical periodontal therapy, the use of subgingival air-polishing with erythritol powder has shown promising results in reducing deep pockets and gingival inflammation. The efficacy of its use as monotherapy in preventing WSLs and gingival inflammation in patients during orthodontic treatment, has not yet been tested. The primary objective of the present study is to compare the effectiveness of an air-polishing device used as monotherapy versus ultrasonic instrumentation (the current gold standard procedure) in preventing white spot lesions (WSL) and gingivitis among young patients undergoing multi-bracketed fixed orthodontic treatment.

NCT ID: NCT05868603 Not yet recruiting - White Spot Lesion Clinical Trials

Effect of Different Remineralization Gels

Start date: May 24, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to treat white spot lesions that occur after orthodontic treatment. Different gels will be used for remineralization. The study will consist of 45 people between the ages of 15-18. 45 people will be divided into 3 groups.

NCT ID: NCT05775250 Completed - White Spot Lesion Clinical Trials

Evaluation of Two Varnishes on the Improvement of White Spot Lesions in Children

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

A randomized control trial evaluating the effect of the Giomer varnish versus fluoride varnish on the color improvement of the white spot lesion in permanent anterior teeth of children aged between 8-14 years by using a spectrophotometer at baseline, after 1 month, 3 months and 6 months

NCT ID: NCT05771077 Completed - White Spot Lesion Clinical Trials

Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite

Start date: June 1, 2022
Phase: Phase 1
Study type: Interventional

Dental caries is a common oral disease. The process of caries formation is a cycle of remineralization and demineralization with various stages being either reversible or irreversible.

NCT ID: NCT05738369 Active, not recruiting - White Spot Lesion Clinical Trials

The Effect of Probiotic Lozenges on White Spot Lesion Development in Orthodontic Patients

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial was to investigate the effect of probiotic lozenges on the development of white spot lesions (WSLs) compared to a positive control, and no treatment.

NCT ID: NCT05738356 Completed - White Spot Lesion Clinical Trials

Evaluation of White Spot Lesion Development Using 3 Orthodontic Adhesive Systems

Start date: December 10, 2021
Phase: N/A
Study type: Interventional

The gaol of this randomized clinical trial was to compare the effect of self-etching primer bonding system and one step adhesive bonding system on the development of white spot lesions (WSLs) during fixed orthodontic therapy in comparison with the conventional 3 step bonding system. All participants will be bonded with similar fixed orthodontic appliances using each type of adhesives for the assigned group. WSLs will be monitored during the orthodontic treatment

NCT ID: NCT05721586 Completed - White Spot Lesion Clinical Trials

Self-assembling Peptide With Sodium Fluoride in Treating White Spot Lesionss in Primary Teeth

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Regenerative medicine-based approaches for caries treatment focus on biomimetic remineralization of initial carious lesions as a minimally invasive therapy using Self-Assembling Peptide P11-4 (CURODONTTM REPAIR) which enhances remineralization of white spot lesions (WSLs). The study aimed to assess clinically the effect of Self Assembling Peptide P11-4 (CURODONTTM REPAIR) + Fluoride varnish (DURAFLOR) versus a 5% fluoride varnish (DURAFLOR) on remineralization of enamel White Spot Lesions in primary teeth.

NCT ID: NCT05710874 Completed - Clinical trials for Orthodontic Appliance Complication

A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.

Start date: September 23, 2016
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare the influence of casein phosphopeptide amorphous calcium phosphate (CPP-ACP), CPP-ACP in combination with fluoride (CPP-ACPF), high fluoride concentration, and conventional fluoride toothpaste on the color and size of white spot lesions (WSLs) in orthodontic patients following bracket removal.

NCT ID: NCT05584878 Not yet recruiting - White Spot Lesion Clinical Trials

Remineralizing Potential of Biomimetic Scaffolds on Enamel White Spot Lesions

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The modern concept in caries treatment focuses on the non-invasive approach and on the biomimetic remineralization of early non-cavitated white spot carious lesions. Recently developed biomimetic scaffolds attempt to remineralize the dental tissues and are more regenerative than reparative.

NCT ID: NCT05550116 Enrolling by invitation - White Spot Lesion Clinical Trials

Clinical Evaluation of White Spot Lesions Treated by S-PRG and ICON

Start date: August 11, 2021
Phase: N/A
Study type: Interventional

Randomized with (1:1) prospective, double-blind, controlled trial. Subjects will be randomized to receive S-PRG and the control group receives ICON.