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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT03973554
Other study ID # 11090
Secondary ID
Status Not yet recruiting
Phase Phase 2
First received
Last updated
Start date October 30, 2019
Est. completion date October 30, 2021

Study information

Verified date June 2019
Source Cairo University
Contact Ruba A El Damarisy, MDS
Phone 01222308685
Email eldamarisyruba@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel white spot lesions.


Description:

The aim of the study is to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel White Spot Lesions using laser fluorescence device scoring from 0 to 99, with daily application time of 3 months and follow up period of 6,9,and 12 months.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 58
Est. completion date October 30, 2021
Est. primary completion date October 30, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 12 Years to 25 Years
Eligibility Inclusion Criteria:

- good oral hygiene

- cooperative patient

- completion of orthodontic therapy

- presence of at least two white spot lesions on the labial surface of six maxillary anterior teeth, that were not present before orthodontic treatment

Exclusion Criteria:

- bad oral hygiene

- lack of patients compliance

- allergy to milk products

- pregnant or lactating women

- presence of dentin caries, restorations, or enamel hypoplasia on maxillary anterior teeth

- presence of periodontal pockets around maxillary anterior teeth

Study Design


Related Conditions & MeSH terms


Intervention

Other:
pearl powder
natural product, support bone and joint health
Drug:
CPP-ACP
Remineralising sugar free dental topical crème, containing bio-available calcium and phosphate

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Ruba Alaa El Din Adel El Damarisy

Outcome

Type Measure Description Time frame Safety issue
Primary caries prevention in enamel white spot lesion caries prevention using laser fluorescence device 12 months
See also
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Terminated NCT04827966 - Remineralization Agents for the Treatment of White Spot Lesions N/A
Completed NCT05757440 - Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions N/A
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Not yet recruiting NCT03930927 - Effect of Self Assembling Peptide on White Spot Lesion Early Phase 1
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Recruiting NCT03823612 - Reminerlization Potential of Innovative Biomimetic Material in Caries White Spot Lesions Phase 4
Completed NCT04401280 - Bioactive Glass in the Treatment of Enamel White Spot Lesions Phase 3
Completed NCT03738839 - A Comparative Assessment of Orthodontic Treatment Outcomes Using the Quantitative Light-Induced Fluorescence Method N/A
Recruiting NCT04994314 - White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial Phase 3
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Active, not recruiting NCT05764187 - Incidence of White Spot Lesions Around Ceramic Brackets Compared With Metal Brackets N/A
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