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Effect of Self Assembling Peptide on White Spot Lesion — regeneration  

White Spot Lesion of Tooth Clinical Trial

Official title:
Evaluation of the Re-mineralizing Effect of Biomimetic Self-Assembling Peptides in Post Orthodontic White Spot Lesions Compared to Fluoride-Based Delivery Systems

Clinical Trial Summary

During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?

Clinical Trial Description

Conservative dentistry no longer prefers the "drill and fill" concept and advocates reversal of lesions via remineralization. . Remineralization is the process of restoring minerals - again, in the form of mineral ions - to the hydroxyapatite latticework structure. It is three-dimensional, and the lost ions must be replaced with ions having the exact same shape, size and the same electrical charge as those lost from the lattice.

Fluoride and self-assembling peptides have been used as adjuncts to enhance remineralization. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03930927
Study type Interventional
Source Cairo University
Contact raneen ahmed gohar, Assistant lecturer
Phone (002)01007331552
Email raneen.aboelgheit@dentistry.cu.edu.eg
Status Not yet recruiting
Phase Early Phase 1
Start date May 1, 2019
Completion date March 1, 2021
View Details
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