Nasal Findings in Reactive Airway Diseases

Wheezing Clinical Trial

— nasalfinding  

Official title:

Nasal Findings in Reactive Airway Diseases

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03131323
• Other study ID #: Assuit universit 17100106
• Status: Not yet recruiting
• Phase: N/A
• First received: April 23, 2017
• Last updated: April 26, 2017
• Start date: June 1, 2017
• Est. completion date: July 1, 2018

Study information

• Verified date: April 2017
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Reactive airway diseases is a common respiratory diseases affecting 1-18% of the population in different countries. It carries a significant burden to children, their families, the healthcare system and the overall community.The purpose of the study is to delineate the prevalence of abnormal nasal finding in wheezy children and evaluate the role of the endoscopic examination of the nose in evaluation and management of a wheezy child.Patients and methods:The study will be conducted as a prospective case series including all children having chest wheezes, aged from two years to eighteen years, attending emergency unit of assuit university children hospital

Description:

Reactive airway diseases is a common respiratory diseases affecting 1-18% of the population in different countries. The worldwide increasing incidence of asthma continues to make it a global health problem . It is one of the major causes of hospitalization among children younger than 15 years of age . It carries a significant burden to children, their families, the healthcare system and the overall community. When combined with shortness of breath, chest tightness and/or cough, it is a bronchial asthma .

Pediatric wheeze be triggered by upper respiratory tract infections . The adenoids are a prominent contributor to chronic rhinitis in the pediatric population. Clinical control of chronic rhinosinusitis may be important to optimize the control of difficult-to-treat asthma. However, the relationship between chronic rhinosinusitis and asthma in children remains largely descriptive .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: July 1, 2018
• Est. primary completion date: July 1, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 2 Years to 18 Years

Eligibility

Inclusion Criteria:

• All children having chest wheezes, aged from two years to eighteen years, attending emergency unit of Assiut University Pediatric Hospital, during the period 1/6/2017 to 1/6/2018. They will be examined in Otolaryngology Department, Assiut University Hospital

Exclusion Criteria:

• Refusal of endoscopic nasal examination by care givers.and patients with definite diagnosis of wheeze (bronchiolitis,pneumonia)

Related Conditions & MeSH terms

• Bronchial Hyperreactivity
• Reactive Airway Disease
• Respiratory Sounds
• Wheezing

Intervention

Procedure:
• • Flexible fiberopticnasopharyngoscope
II- Equipments: Flexible fiberopticnasopharyngoscope, 2.7 mm in diameter and fiberoptic light cable. The camera: fitted with Three-CCD (Charged Couple Device) sensors. A high resolution monitor. A recording unit. III- Positioning:Infants and small children have to be held by a parent or an adult. Older children and adolescents usually tolerate office flexible nasopharyngoscopy once the procedure is explained. If office flexible nasopharyngoscopy failed because the child is not cooperative or if there is excessive secretions, general anesthesia may be required [8]. IV- Technique: Lubricant gel will be applied to the tip of the endoscope which will be now will be passed along the floor of the nose, between the inferior turbinate and the nasal septum, till it reaches the nasopharynx. Now the entire nose and the nasopharynx could be thoroughly examined and any abnormal findings could be detected and documented.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	nasal findings in reactive airway diseases	the prevalence of abnormal nasal finding in wheezy children	one year