Wheeze Clinical Trial
Official title:
Treating Wheezing in Children With Hypertonic Saline (TWICS)
Hypothesis: substitution of nebulized 3% NaCl (HS) for the standard normal saline (NS) used
in bronchodilator therapy for acute viral wheezing in all children under age 6 years will
provide superior symptom relief leading to decreased admission rates from the Emergency
Department.
The study will test the efficacy of frequent doses of inhaled bronchodilator co-administered
with either 3% hypertonic saline (HS, study group) or 0.9% normal saline (NS, control group)
in a prospective, double blind, randomized controlled, multi-centre clinical trial of
children under age 6 years presenting to the ED with acute viral-associated wheezing.
the brief summary captures the essence of the study ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02743663 -
The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
|
||
| Recruiting |
NCT02496468 -
Pediatric Arm of DZL All Age Asthma Cohort
|
||
| Withdrawn |
NCT02319564 -
Combined Glucocorticoid Adrenergic Therapy For Wheezy Preschool Children
|
Phase 4 |