Optimizing the Treatment Strategy for Age-related Macular Degeneration — OnP2  

Wet Macular Degeneration Clinical Trial

Official title: A Randomised Controlled Trial Testing the Efficacy of the Treatment Strategy Observe-and-Plan Against Standard Treat-and-Extend in a Population of Newly Referred Patients With Age-related Macular Degeneration.

Status Recruiting

Clinical Trial Summary

The purpose of this study is to compare two different treatment protocols for wet macular degeneration; the new protocol called "Observe and Plan" against the current standard protocol "Treat and Extend". Studies suggest that patients achieve equally good visual acuity with fewer controls and that they are more satisfied with the new protocol.

Clinical Trial Description

The purpose of the study is to test a new treatment protocol for wet macular degeneration, called "Observe and Plan", against today's standard protocol "Treat and Extend". Studies suggest that the individual treatment interval can be achieved earlier with "Observe-and-Plan" and that a proportion of patients do not need more than 3 injections, ie the loading dose. The other advantages seem to be that patients achieve good visual acuity with fewer controls and are more satisfied with the new protocol, which will be beneficial to both patients and health care. To our knowledge, no randomized controlled trial has tested this before. ;

Related Conditions & MeSH terms

• Macular Degeneration
• Wet Macular Degeneration

• NCT number: NCT04420923
• Study type: Interventional
• Source: St. Olavs Hospital
• Contact: Margrete Sætre Hanssen, MD
• Phone: +47 91871727
• Email: margrete.saetre.hanssen@ntnu.no
• Status: Recruiting
• Phase: N/A
• Start date: June 8, 2020
• Completion date: June 30, 2025