Clinical Trials Logo

Werner Syndrome clinical trials

View clinical trials related to Werner Syndrome.

Filter by:
  • None
  • Page 1

NCT ID: NCT05847179 Not yet recruiting - Werner Syndrome Clinical Trials

Phase 2, Open-Label Study to Evaluate the Safety and Tolerability of Progerinin in Werner Syndrome

Start date: January 1, 2025
Phase: Phase 2
Study type: Interventional

This is a Phase 2, open-label study to A Phase 2, Open-Label Study to Evaluate the Safety and Tolerability of Progerinin for the Treatment of Bone Mineral Density (BMD) Loss in Subjects with Typical Werner Syndrome. There will be up to 5 subjects that will receive treatment with Progerinin twice daily for approximately 1 year.

NCT ID: NCT04512963 Completed - Clinical trials for Hutchinson-Gilford Progeria Syndrome

Phase I Study of Progerinin in Healthy Volunteers

Start date: August 24, 2020
Phase: Phase 1
Study type: Interventional

PRG-PRO-001 is a Phase I, Randomized, Double-blind, Placebo-Controlled, Single Ascending Dose (SAD) Study including a food interaction study, followed by a Multiple Ascending Dose (MAD) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Profile of Progerinin in Healthy Volunteers. This is a first-in-human study. The study aims to determine the safety and tolerability of Progerinin after single and multiple doses in healthy volunteers and to evaluate the pharmacokinetics (PK) of Progerinin after single and multiple dose administrations in healthy volunteers.

NCT ID: NCT00004815 Completed - Werner's Syndrome Clinical Trials

Descriptive Study of Recombinant Human Insulin-Like Growth Factor for Osteoporosis in Werner's Syndrome

Start date: May 1992
Phase: N/A
Study type: Interventional

OBJECTIVES: I. Assess the safety and efficacy of recombinant human insulin-like growth factor 1 in a patient with Werner's syndrome and osteoporosis.