Cardiorespiratory Responses to Treadmill Running at Different Slopes

Well-trained Athletes Clinical Trial

Official title:

Comparison of Cardiorespiratory Responses to Treadmill Running at Different Slopes in Well-trained Athletes

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03946215
• Other study ID #: 7038
• Status: Completed
• Phase: N/A
• Start date: September 1, 2018
• Est. completion date: December 17, 2018

Study information

• Verified date: May 2019
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is: i) to determine if maximal oxygen uptake in downhill running is significantly different versus flat or uphill running, and ii) to compare cardiorespiratory and muscle fatigue responses to uphill vs flat and downhill running at similar running velocity and similar metabolic power. The investigators hypothesized that maximal oxygen uptake will be lower in downhill running. The investigators also anticipate attenuated cardiorespiratory and muscle fatigue responses to downhill running when compared to flat or uphill running performed at similar velocity but not when the comparison is done at similar metabolic power.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 8
• Est. completion date: December 17, 2018
• Est. primary completion date: December 17, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• to be a well-trained runner with a VO2max > à 55 ml/kg/min

• nonsmoker or stopped smoking for 5 years

• BMI < 25

• affiliation to the social health insurance scheme

• signing an informed consent form.

Exclusion criteria:

• impossibility to give the subject enlightened information (subject in emergency situation, difficulties in understanding the study, ...);

• subject under the protection of justice

• subject under guardianship or curatorship

• contraindication to the practice of physical and sport activities

• lower limbs musculotendinous or articular problems

• respiratory, cardiovascular or metabolic pathology

• drug treatment in progress and impossibility to stop it within 7 days before the beginning of the study

Related Conditions & MeSH terms

• Cardiorespiratory Responses
• Well-trained Athletes

Intervention

Other:
• Each participant will perform:
Part 1: Maximal incremental tests will require running at fixed slopes (+15%, 0% -15%) for stages (2min duration) of increasing velocities (0.5, 1 and 1.5 km/h) Part two: submaximal running tests will require running at constant velocity (80% VO2max uphill; 80%VO2max downhill and downhill at similar velocity as uphill)

Locations

Country	Name	City	State
France	Les Hôpitaux Universitaires de Strasbourg	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Peak oxygen	The peak oxygen uptake will be collected during downhill, flat and uphill running	15 minutes