Critical Care Clinical Trial
Official title:
The Effect of T-Tube and Pressure Support on Cardiorespiratory Variables and Heart Rate Variability During Weaning From Mechanical Ventilation
The discontinuation of mechanical ventilation (MV) and the recovery of spontaneous breathing can lead to important cardiovascular alterations due to changes in the intrathoracic pressure. The autonomic modulation assessed through heart rate variability (HRV) during weaning from MV and its impact on cardiorespiratory variables has not been well elucidated yet. To evaluate the effect of T-tube (TT) and pressure support ventilation (PSV) during weaning from MV on cardiorespiratory variables and heart rate variability.
Thirty patients who had received MV for ≥ 48 hours and who met the criteria for weaning were assessed. Two different weaning methods were used and randomization was performed to choose one of the following sequences (baseline, PSV, rest, TT; or baseline, TT, rest, PSV). HRV was assessed by heart rate spectral analysis during MV, PSV, and TT. Each intervention lasted 30 minutes and there was a 30-minute rest period between the interventions. At the end of each period of time, the following cardiorespiratory variables were analyzed: respiratory rate (f), minute ventilation (VE), tidal volume (VT), rapid shallow breathing index (f/VT), peripheral oxygen saturation (SpO2), heart rate (HR) and blood pressure. In the HRV, the total spectral power (TP), the low frequency (LF) and the high frequency (HF) components, and the ratio between the low/high frequency (LF/HF) components were calculated. ;
Time Perspective: Cross-Sectional
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05114551 -
ICU Predictive Score of WEaning Success in Patients At Risk of Extubation Failure
|
||
| Completed |
NCT05547646 -
The Prevalence of Healthcare-associated Infection in Medical Intensive Care Units in Tunisia
|
||
| Recruiting |
NCT03697785 -
Weaning Algorithm for Mechanical VEntilation
|
N/A | |
| Completed |
NCT02922101 -
Evaluation of the Effectiveness of an Audit and Feedback Intervention With Quality Improvement Toolbox in Intensive Care
|
N/A | |
| Completed |
NCT02902783 -
DONATE-Pilot Study on ICU Management of Deceased Organ Donors
|
||
| Completed |
NCT01857986 -
Evaluating Air Leak Detection in Intubated Patients
|
N/A | |
| Completed |
NCT01885442 -
TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients
|
N/A | |
| Recruiting |
NCT05518955 -
VR Integrated Into Multicomponent Interventions for Improving Sleep in ICU
|
N/A | |
| Recruiting |
NCT03810768 -
Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness
|
||
| Completed |
NCT03295630 -
Validity of an Actigraph Accelerometer Following Critical Illness
|
N/A | |
| Recruiting |
NCT05556811 -
HEaling LIght Algorithms for the ICU Patient
|
N/A | |
| Recruiting |
NCT05702411 -
Air Stacking Technique For Pulmonary Reexpansion
|
N/A | |
| Completed |
NCT02741453 -
Bilateral Internal Jugular Veins Ultrasound Scanning Prior to CVC Placement
|
N/A | |
| Recruiting |
NCT04979897 -
Impact on Mental, Physical, And Cognitive Functioning of a Critical Care sTay During the COVID-19 Pandemic
|
||
| Completed |
NCT05281224 -
Ventilator Tube Holder for Patients With a Tracheostomy
|
||
| Withdrawn |
NCT02970903 -
VitalPAD: an Intelligent Monitoring and Communication Device to Optimize Safety in the PICU
|
N/A | |
| Recruiting |
NCT02587273 -
The Pharmacokinetics of Fentanyl in Intensive Care Patients
|
Phase 4 | |
| Completed |
NCT02661607 -
Point of Care Echocardiography Versus Chest Radiography for the Assessment of Central Venous Catheter Placement
|
N/A | |
| Completed |
NCT01479153 -
Venous Site for Central Catheterization
|
N/A | |
| Recruiting |
NCT06110390 -
High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients
|
N/A |