Performance of CAST (Cellular Antigen Stimulation Test) in Patients With Wasp Venom Allergy: Evaluation of Neutralizing IgG Subclasses

Wasp Venom Allergic Patients Clinical Trial

Official title:

Performance of CAST (Cellular Antigen Stiumulation Test)in Patients With Wasp Venom Allergy. Evaluation of Neutralizing IgG Subclasses

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT00794287
• Other study ID #: ZU-AgNT-004
• Status: Withdrawn
• Phase: N/A
• First received: November 19, 2008
• Last updated: June 3, 2015
• Start date: January 2009

Study information

• Verified date: June 2015
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: UZurich
• Study type: Observational

Clinical Trial Summary

To determine which subclass of IgG in the serum of patients undergoing SIT against wasp venom is able to neutralize the allergen, and therefore to prevent a positive CAST

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. primary completion date: December 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 75 Years

Eligibility

Inclusion criteria:

• male and female patient with allergy to wasp venom grade III and IV according to H.L. Müller

• 18-75 years

• planned SIT against wasp venom or finished 5 years SIT against wsp venom (10/10)

Exclusion criteria:

• oral corticosteroids

• chromogycin

• ketotifen

• immunosuppressive drugs within the last 2 years

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Wasp Venom Allergic Patients

Intervention

Other:
• Taking blood samples
No intervention is done. Only blood samples are taken.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland,