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Clinical Trial Summary

The purpose of this study is to evaluate the efficiency of an oral regimen in newly diagnosed Waldenström macroglobulinemia: thalidomide plus cyclophosphamide and dexamethasone following by thalidomide and prednisone maintenance therapy.


Clinical Trial Description

Enrolled patients will accept maximum 8 cycles of thalidomide plus cyclophosphamide and dexamethasone. if a partial remission response or better is achieved, thalidomide plus prednisone maintenance therapy will be given for no more than two years. ;


Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02844309
Study type Interventional
Source Institute of Hematology & Blood Diseases Hospital
Contact Shuhua Yi, Doc
Phone 86-22-23909106
Email yishuhua@ihcams.ac.cn
Status Recruiting
Phase Phase 4
Start date May 2016
Completion date May 2020

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