Human Papillomavirus (HPV) Clinical Trial
Official title:
A Phase 2, Randomized, Open Label, Efficacy Study of VGX-3100 Delivered Intramuscularly Followed by Electroporation With CELLECTRAâ„¢ 2000 Alone or in Combination With Imiquimod, for the Treatment of HPV-16 and/or HPV-18 Related High Grade Squamous Intraepithelial Lesion (HSIL) of the Vulva
The purpose of this study is to test the safety and efficacy of an investigational immunotherapy VGX-3100, in combination with a study device, to treat women with vulvar high-grade squamous intraepithelial lesion (HSIL) [vulval intraepithelial neoplasia 2 or 3 (VIN 2 or VIN 3)] associated with human papilloma virus (HPV) types 16 and/or 18. VGX-3100 is being assessed as an alternative to surgery with the potential to clear the underlying HPV infection. For more information visit our study website at: www.VINresearchstudy.com
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT02540928 -
AMG 319 in HPV Positive and Negative HNSCC
|
Phase 2 | |
Not yet recruiting |
NCT05727033 -
Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections
|
N/A | |
Completed |
NCT03111251 -
Multi-component Interventions to Increase HPV Vaccination in a Network of Pediatric Clinics
|
N/A | |
Withdrawn |
NCT04849377 -
RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC
|
Phase 2 | |
Completed |
NCT02873741 -
New Strategies to Assess Anal Cancer Risk In Women
|
||
Completed |
NCT01188850 -
Fourth Dose of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + EP in Adult Females Previously Vaccinated With Three Doses of VGX-3100
|
Phase 1 | |
Completed |
NCT02524223 -
Prevalence of HPV Transmission During Medically Assisted Procreation Procedures
|
N/A | |
Recruiting |
NCT01197079 -
Utilization of Human Papillomavirus (HPV) Vaccine Among Young Men Who Have Sex With Men (MSM) and Parents of Boys (Aged 9 to 18 Years)
|
N/A | |
Recruiting |
NCT05539638 -
The Role of Circulating Tumour DNA in Head and Neck Cancer
|