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Clinical Trial Summary

1. To compare the recurrence rate between the use of laser vaporization and ultrasonic surgical aspiration in the treatment of vulvar and vaginal dysplasias 2. To compare healing related complications, post-operative pain, and scarring between the two procedures.


Clinical Trial Description

First line of treatment for vulvar intraepithelial neoplasia (VIN) and vaginal intraepithelial neoplasia (VAIN) is not well defined. Laser vaporization and ultrasonic surgical aspiration are both accepted surgical modalities used in the treatment of vulvar and vaginal dysplasias, however no prospective study has been done to compare the two procedures. The specific aims of this research study include: 1. To compare the recurrence rate between the use of laser vaporization and ultrasonic surgical aspiration in the treatment of vulvar and vaginal dysplasias in a prospective, multi-institutional, randomized clinical trial. 2. To compare healing related complications, post-operative pain, and scarring between the two procedures. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00394758
Study type Interventional
Source University Hospitals Cleveland Medical Center
Contact
Status Completed
Phase Phase 3
Start date January 1, 2000
Completion date December 31, 2005

See also
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Completed NCT03180684 - Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) Phase 2
Active, not recruiting NCT03792516 - Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3) Phase 1