Evaluation of Bleeding Score in Egyptian Patients With vWD Type I and Correlate it With Laboratory Parameters

Von Willebrand Disease, Type 1 Clinical Trial

Official title:

Assessing the Bleeding Severity in Type I Von Willebrand Patients Using the International Society on Thrombosis and Hemostasis Bleeding Assessment Tool ( ISTH-BAT) Questionnaire

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03915873
• Other study ID #: BS in VWD
• Status: Not yet recruiting
• Start date: December 1, 2019
• Est. completion date: March 1, 2021

Study information

• Verified date: September 2019
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Applying the ISTH-BAT questionnaire on Egyptian patients with type I VWD aiming to correlate the BS with the laboratory findings

Description:

The clinical phenotype of the disease is variable and tends to be mild in type 1 vWD, whereas it shows serious bleeding manifestations in types 2 and 3. Overall, the symptoms reported in vWD include easy bruising, epistaxis, gastrointestinal bleeding, excessive menstrual bleeding, postpartum haemorrhage, and excessive bleeding after surgical operation and minor wounds.However, A distinctive bleeding history is a prerequisite for the diagnosis of any bleeding disorder and should guide further laboratory investigations In an attempt to standardize the diagnostic criteria of VWD, a bleeding questionnaire and a bleeding score were developed The combination of a standardized bleeding questionnaire and a well-defined interpretation grid (for the computation of the final (BS) has been referred to as a Bleeding Assessment Tool (BAT).

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 20
• Est. completion date: March 1, 2021
• Est. primary completion date: December 1, 2020
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• type 1 vWD patients

• healthy subjects with no known problem with bleeding or bruising were also recruited

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Von Willebrand Disease, Type 1
• Von Willebrand Diseases

Intervention

Diagnostic Test:
• The von Willebrand Antigen level
blood sample

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the International Society on Thrombosis and Hemostasis-Bleeding Assessment Tool (ISTH-BAT)	Questionnaire minimum score ranges from 0 to 10 whereas maximum score ranges from 20 to 30	one year