Effects of Octanoic Acid for Treatment of Essential Voice Tremor

Voice Tremor Clinical Trial

Official title: Effects of Octanoic Acid for Treatment of Essential Voice Tremor

Status Completed

Clinical Trial Summary

Essential voice tremor is a neurological condition that produces a regular, shaking quality in the voice. One form of drug treatment that produces some improvement in tremor of the hands is octanoic acid, which is a food additive that is similar to alcohol. Research suggests that octanoic acid may reduce tremor in the hands/arms with few side effects and no intoxication effects. This study will determine whether octanoic acid may be useful for reducing tremor when it affects the voice. Researchers are hypothesizing that octanoic acid will reduce the effects of tremor on the voice.

Clinical Trial Description

Background:

• Essential tremor of the voice produces regular shaking and hoarseness in the voice, making it difficult speech difficult to understand

• Several previous studies have found that octanoic acid and octanol, which are related to alcohol, can improve tremor in some people without producing many side effects and without producing intoxication

• Researchers are interested in determining whether octanoic acid can improve tremor that affects the voice

Objectives:

• To determine the effects of octanoic voice using voice recordings and listener ratings of voice

• To determine the effects of octanoic acid on level of voice disability experienced by people with essential voice tremor ;

Related Conditions & MeSH terms

• Essential Tremor
• Essential Tremor of Voice
• Essential Voice Tremor
• Tremor
• Vocal Tremor
• Voice Tremor

• NCT number: NCT01864525
• Study type: Interventional
• Source: Syracuse University
• Status: Completed
• Phase: Phase 1/Phase 2
• Start date: July 2013
• Completion date: March 31, 2017