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Voice Disorders clinical trials

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NCT ID: NCT04853680 Recruiting - Thyroid Cancer Clinical Trials

Effect of Anti-adhesion Barrier on the Voice Quality After Thyroidectomy.

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

To determine whether the use of anti-adhesion barrier after thyroid surgery can prevent the voice changes after surgery, using objective voice-related indicators.

NCT ID: NCT04846413 Recruiting - Neurologic Disorder Clinical Trials

Voice Analysis in Patients With Neurologic Diseases

Start date: September 1, 2021
Phase:
Study type: Observational

In this observational pilot study, the investigators will record and assess voice samples from healthy participants and those participants affected by neurologic diseases to evaluate possible differences in voice features.

NCT ID: NCT04766658 Completed - Voice Disorders Clinical Trials

A Study to Evaluate Effects of Gargle Phonation in Voice

Start date: January 29, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess subjects with muscle tension dysphonia for perceived effort and acoustic effects of gargle phonation compared to baseline and a sham water swallow.

NCT ID: NCT04708600 Completed - Gender Dysphoria Clinical Trials

Effectiveness of Speech Therapy in Trans Women.

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

One of the greatest hurdles in the transition of transgender persons is that voice, speech and communication are not congruent with the desired gender. Since hormone treatment does not affect the voice in male-to-female transgender persons (trans women), speech therapy is the treatment of choice to develop a more feminine communication. Speech therapy must focus on aspects of communication that play an important role in listener perceptions of the speakers gender. Results of a systematic review and meta-analysis showed that those aspects are primarily fundamental frequency of the voice and resonance. However, effectiveness studies of speech interventions in transwomen are extremely limited and show methodological limitations. The purpose of this project is to investigate the short-term and longterm impact of speech exercises for pitch and resonance on (a) acoustic voice characteristics, (b) listener perceptions of femininity using a visual analogue scale and binary gender identification (male versus female voice), and (c) self-perception and psychosocial functioning in trans women using a randomized sham-controlled trial and cross-over design.

NCT ID: NCT04638361 Completed - Clinical trials for Surgery--Complications

Laryngeal Disorders After Childhood Cardiac Surgery

RECUP-TML
Start date: August 26, 2021
Phase:
Study type: Observational

Laryngeal disorders after childhood cardiac surgery is a complication well described in the literature. However, the long term progression of the affected children has never been studied (all the studies stopped before 2 years of follow up).

NCT ID: NCT04584658 Recruiting - Covid19 Clinical Trials

Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)

DYADS
Start date: September 15, 2020
Phase:
Study type: Observational

This study examines the presence, severity and natural history of dysphagia and dysphonia in the post-extubation and severely unwell COVID-19 patient.

NCT ID: NCT04525066 Completed - Clinical trials for Head and Neck Squamous Cell Carcinoma

Phonosurgical Augmentation After Laser Resection of Early Glottic Carcinoma

Start date: August 13, 2013
Phase: Phase 2
Study type: Interventional

Objectives: Transoral Laser Microsurgery (TLM) is widely used in for treating T1/T2 glottic cancers. Hyaluronic acid (HA) is a safe and commonly-used injectable in vocal cord augmentation. We report on the results of our single-blinded, randomized-controlled trial (RCT) investigating the impact of intra-operative HA injection on voice outcomes in early glottic cancer. Methods: Patients with T1/T2 glottic cancers were randomized to the treatment group (n=14) receiving HA injection to the unaffected cord during TLM; or the control group, receiving no injection (n=16). All patients had a Voice Handicap Index-10 (VHI-10) questionnaire and a Maximum Phonation Time (MPT) measurement preoperatively and at 3, 12 and 24 months post-operatively. Mean change in VHI-10 and MPT, between pre-operative and post-operative time points, and between the time points, were compared. Survival estimates were also calculated.

NCT ID: NCT04513392 Not yet recruiting - Voice Disorders Clinical Trials

Comparison of BL and KTP Laser for Treatment of Benign Vocal Fold Lesions

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Preliminary investigations suggest that a novel blue light (BL) laser with a wavelength of 445nm is comparable to the commonly utilized KTP laser (532nm) for treatment of laryngeal pathologies. An animal study by the Principal Investigators showed that the blue light laser results in significantly less vocal fold scarring compared to the KTP laser, suggesting that the blue light laser may be a better instrument for treating vocal fold disease. However, there are no clinical studies directly comparing the two lasers on treatment of vocal fold pathology. The goal of the proposed study is to directly compare treatment outcomes of the BL laser and KTP laser for benign vocal fold lesions. All laser treatments will be performed in the office under local anesthesia as per standard of care. Outcome variables of interest will be compared between groups, including Voice Handicap Index-10 (VHI-10) score (measured at baseline, 1 week, 1 month, and 3 months post procedure), laryngeal stroboscopic findings (1 and 3 months post procedure), and intra-operative pain. This study will provide support that the blue light laser is a comparable alternative to the KTP laser and allow the addition of this novel laser to the armamentarium for treating vocal fold diseases.

NCT ID: NCT04107337 Active, not recruiting - Dysodia Clinical Trials

Effect of Vocal Exercises With Straw on Aerodynamic Parameters of Voice (Pressure, Flow) in Dysodic Singers With Nodules

DYSODIE
Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Singers are over-represented in phoniatric consultations; they present increased risk of developing voice disorders. The most common lesion found in singers is nodule. It comes from vocal straining characterized by the use of a pressed phonation mode, resulting in an increase subglottal pressure and a decrease flow rate. Voice therapy aims to restore a more relaxed phonation. There is a growing interest in semi-occluded vocal tract exercises with a straw in therapy; they have positive effects, particularly in terms of aerodynamic parameters such as subglottal pressure and oral airflow. After these exercises, subglottal pressure decreases and oral airflow increases. In other words, patient adopts a more relaxed phonation mode. Several studies have investigated the effect of these straw exercises on dysphonic patients i.e. on speaking voice; no study to date has explored the effect of these exercises on dysodic subjects i.e. on singing voice. The aim of this study is to evaluate the impact of straw exercises compared to open-mouth exercises on aerodynamic parameters in dysodic women singers with nodules.

NCT ID: NCT04096352 Completed - Voice Disorders Clinical Trials

Virtual Reality in Teachers' Vocal Motor Behavior Acquisition (VirtuVox)

VirtuVox
Start date: September 29, 2019
Phase: N/A
Study type: Interventional

Scientific literature supports that teachers are at greater risk for voice disorders than the general population. In the classroom, the teacher's voice represents the main communication tool. Optimal voice use is indispensable to ensure effective teaching and preserve the teacher's vocal health. This project investigates how virtual reality (VR) facilitates the learning of effective vocal skills and their application in real-world contexts. Based on acoustic analyses and self-assessment scales, the investigators compare 100 future teachers randomly assigned in two groups. The experimental group (n=50) receives a voice training by VR simulations and voice information. The control group (n=50) only receives voice information.