Clinical Trials Logo

Vocal Fold; Scar clinical trials

View clinical trials related to Vocal Fold; Scar.

Filter by:
  • Recruiting  
  • Page 1

NCT ID: NCT05627648 Recruiting - Vocal Fold Scar Clinical Trials

Phase 3 Study of KP-100LI in Subjects With Vocal Fold Scar

Start date: November 24, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the efficacy and safety of KP-100LI, a intracordal formulation containing recombinant human dHGF as the active pharmaceutical ingredient, for voice function improvement therapy in patients with vocal fold scar (including vocal fold sulcus).

NCT ID: NCT04290182 Recruiting - Dysphonia Clinical Trials

A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring

Start date: March 2020
Phase: Phase 1/Phase 2
Study type: Interventional

The overall aim of the project is to develop a new method for treatment of untreatable severe hoarseness due to vocal fold scarring by local injection of autologous mesenchymal stromal cells (MSC). At present there is no lasting effective treatment for this condition which results in personal suffering, and often extended sick leave, change of work or unemployement for the patients. Based on the previous results the investigators expect the autologous MSC product KI-MSC-PL-204 to be a new effective treatment without side effects for many patients with severe hoarseness or aphonia due to vocal fold scarring.