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Vocal Fold Palsy clinical trials

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NCT ID: NCT04700566 Recruiting - Vocal Fold Palsy Clinical Trials

Allograft Adipose Injectable for Vocal Fold Paralysis

Start date: May 16, 2022
Phase: Phase 3
Study type: Interventional

Renuva is allograft adipose matrix commonly used as a filler in cosmetic procedures. The investigators are studying this material as an injectable in the vocal fold to treat glottic insufficiency. Currently, many products can be used as an injectable in the vocal fold to correct glottic insufficiency such as carbomethycellulose, hyaluronic acid, collagen derivatives and calcium hydroxyapatite amongst others. An ideal injectable would not impair the fibroelastic property of the vocal fold tissues and would integrate within the tissue of the vocal fold. Since Renuva has the property of stimulating adipogenesis by using growth factor and collagen, the investigators believe it could represent a good option in terms of safety and efficacy for vocal fold augmentation. This study will assess the safety and efficacy of Renuva as a vocal fold injectable to treat glottic insufficiency.

NCT ID: NCT01501526 Recruiting - Vocal Fold Palsy Clinical Trials

Unusual Clinical Findings of Herpes Esophagitis

Start date: October 2011
Phase: N/A
Study type: Observational

Herpes esophagitis presents a clinical diagnostic challenge. The investigators report the first case of herpes esophagitis presenting as vocal fold palsy in an immunocompetent host. The investigators case highlights the importance of performing a detailed laryngoscopic examination in any patient with prolonged husky voice.