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Vocal Cord Paralysis clinical trials

View clinical trials related to Vocal Cord Paralysis.

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NCT ID: NCT03966183 Completed - Clinical trials for Unilateral Vocal Cord Paralysis

Early UVFP Management Based on Neurological Evidences (ION-UVFP) - Preliminary Study

Start date: June 15, 2019
Phase:
Study type: Observational [Patient Registry]

The purpose of this preliminary study is to help clarify our hypotheses for the longitudinal study by investigating the relationship between vocal cord paralysis and central auditory processes and thus the interpretation of auditory inputs into the central nervous system.

NCT ID: NCT03906877 Completed - Clinical trials for Unilateral Vocal Cord Paralysis

Early UVFP Management Based on Neurological Evidences (UVFP = Unilateral Vocal Fold Paralysis)

IONS-UVFP
Start date: November 15, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to understand how early intervention could impact reinnervation of the recurrent laryngeal nerve (which innervates the vocal cord), recovery of mobility of the paralyzed vocal cord and / or vocal recovery in the case of unilateral vocal fold paralysis. To achieve this goal we must therefore carry out a complete outcomes assessment of different intervention methods (voice therapy and injection laryngoplasty), which are offered to UVFP (unilateral vocal fold paralysis) patients in the early stage (< 3 months). Their respective impacts on the central and peripheral nervous system and on the voice quality will be assessed, taking into account factors related to the severity of the paralysis.

NCT ID: NCT03882450 Completed - Dysphagia Clinical Trials

Universal Screening for Vocal Fold Motion Impairment in Children Undergoing Congenital Cardiac Surgery

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how often heart or chest surgery in children leads to problems with the movement of the vocal folds.

NCT ID: NCT03864757 Completed - Clinical trials for Paralysis, Unilateral, Vocal Cord

APrevent Vocal Implant System (VOIS) for Adjustable Treatment of Unilateral Vocal Fold Paralysis (UVFP)

Start date: July 5, 2018
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate pre- and intraoperative voice quality, the degree of vocal fold closure and the Maximum Phonation Time (MPT), first determined after temporary APrevent® VOIS implantation and then after permanent existing product implantation.

NCT ID: NCT03790956 Completed - Dysphonia Clinical Trials

Silk Protein Microparticle-based Filler for Injection Augmentation

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

This study will investigate the safety and efficacy of a silk protein microparticle-based filler for vocal fold injection augmentation to treat dysphonia/dysphagia secondary to vocal fold paralysis. Participants will receive one injection and follow-up for a planned period of 12 months.

NCT ID: NCT03727217 Completed - Thyroidectomy Clinical Trials

Performance of Ultrasound in the Early Diagnosis of Vocal Cords Paralysis

PECV
Start date: July 10, 2018
Phase: N/A
Study type: Interventional

Thyroid and parathyroid surgery concerns around 50 000 patients a year in France. One of its main complications is paralysis of vocal cords, and the consequences can be serious. In this study, the main gold is to evaluate diagnostic performances of ultrasound for an early diagnosis (as soon as awakening of the patient) of vocal cords paralysis in the post-operative period in order to prevent at best complications.

NCT ID: NCT03692494 Not yet recruiting - Dysphonia Clinical Trials

The Effects of Adding Expiratory Muscle Strength Training in Voice Therapy

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Evaluate if adding expiratory muscle strength training to traditional voice therapy for individuals with dysphonia due to glottal insufficiency improves maximal expiratory pressure, acoustic and aerodynamic measures (i.e. amplitude, maximum phonation time, peak expiratory flow), and voice related quality of life.

NCT ID: NCT03634956 Recruiting - Clinical trials for Vocal Cord Paralysis

Effect of IONM on Efficacy and Safety Using Sugammadex in Thyroid Surgery

Start date: August 14, 2018
Phase: N/A
Study type: Interventional

Thyroidectomy is a frequently performed surgeon by the head and neck and endocrine surgeons. In recent years, surgical techniques and technological developments have resulted in a significant reduction in complication rates. Despite these advances, there is still a great deal of anxiety about the sound problems that can be experienced in patients after surgery. In the past years,the investigators have tried to prevent recurrent nerve paralysis by using intraoperative nerve monitoring (IONM). The use of IONM has begun to be preferred by many surgeons in the investigator's country. However, the use of IONM decreases the number of recurrent nerve paralysis are still being discussed and many studies have been done. In this study, it is aimed to prevent the formation of recurrent nerve paralysis in order to safely carry out the IONM by removing the effects of neuromuscular blockade drugs using sugammadex sodium medicine in the thyroidectomy operations.

NCT ID: NCT03553342 Recruiting - Clinical trials for Recurrent Paralysis of Vocal Cords

Efficacy of Oral Corticosteroid Therapy in Recurrent Paralyzes After Thyroidectomy

Start date: September 11, 2018
Phase: Phase 3
Study type: Interventional

Thyroidectomy is a common surgical procedure in France. Recurrent paralysis is one of the main complications. Oral corticosteroid therapy are frequently used at a dosage of 1mg/kg for seven days, in case of recurrent paralysis to obtain remobilization as early as possible. The main objective is to evaluate the efficacy of oral corticosteroid therapy in remobilization of vocal cords at seven days in patients with unilateral recurrent paralysis after thyroidectomy.

NCT ID: NCT02996526 Completed - Vocal Cord Paresis Clinical Trials

The Incidence and Impact of Vocal Cord Dysfunction In Patients Undergoing Thoracic Surgery

Start date: September 1, 2016
Phase:
Study type: Observational [Patient Registry]

Population-based single centre, blinded, prospective cohort study of the impact of recurrent laryngeal nerve (RLN) injury on Thoracic Surgery patients. The principal outcome of interest is the effect of RLN injury on respiratory complications. Voice, swallowing, cardiac and mortality outcomes will also be determined.