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Clinical Trial Summary

The goal of this clinical trial is to assess the efficacy and safety or a revised weight band tafenoquine dose in vivax malaria patients. The main question[s] it aims to answer are: - is a revised weight-based TQ regimen (TQRevised: target dose 7.5mg/kg) non-inferior to high dose primaquine (7mg/kg over 7 days) - is a revised weight-based TQ regimen (TQRevised: target dose 7.5mg/kg) superior to fixed dose tafenoquine (300mg) - is the tolerability and safety of TQRevised acceptable - is TQRevised acceptable and feasible Participants will receive a tafenoquine target dose 7.5mg/kg in weight bands. Researchers will compare this to patients receiving a fixed dose tafenoquine and high dose primaquine to see if safe and effective.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06148792
Study type Interventional
Source Menzies School of Health Research
Contact Hellen Mnjala
Phone +610889468675
Email hellen.mnjala@menzies.edu.au
Status Not yet recruiting
Phase Phase 3
Start date April 1, 2024
Completion date March 1, 2027

See also
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