Vitreous Fragments Length After Pars Plana Vitrectomy

Vitreous Disorder Clinical Trial

Official title:

Vitreous Fragments Length After Pars Plana Vitrectomy

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04570007
• Other study ID #: 2/2020
• Status: Recruiting
• Start date: September 20, 2020
• Est. completion date: December 10, 2021

Study information

• Verified date: September 2021
• Source: Ospedale Policlinico San Martino
• Contact: Tommaso Rossi
• Phone: +393482645034
• Email: tommaso.rossi024[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To measure vitreous collagen fragments length after pars plana vitrectomy performed at different cut rates

Description:

Pars plana vitrectomy consists in the removal of vitreous obtained with a vitreous cutter. The instruments attracts vitreous in its port through active suction and cuts with a blade at different cut rates. There is no consensus as to which cut rate would be ideal in order to minimize traction, neither there is agreement on whether increasing cut rates generate shorter collagen fragments or the fluid turbulence creates unpredictable flows at the port generating fragments of different length.

The investigators plan to gather vitreous cut at 1,000, 2,000, 4,000, 8,000 and 16,000 cuts per minute and measure vitreous collagen average length

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 25
• Est. completion date: December 10, 2021
• Est. primary completion date: October 30, 2021
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• patient undergoing pars plana vitrectomy for:

• macular pucker

• macular hole-

• retinal detachment

• age >18

Exclusion Criteria:

• unwilling to participate

• previous trauma

• vitreous haemorrhage

Related Conditions & MeSH terms

• Vitreous Anomalies
• Vitreous Disorder

Intervention

Procedure:
• Pars Plana Vitrectomy
removal of vitreous with vitreous cutter

Locations

Country	Name	City	State
Italy	IRCCS Policlinico San Martino	Genova	RM

Sponsors (1)

Lead Sponsor	Collaborator
Ospedale Policlinico San Martino

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	collagen fragment molecular weigth	collagen passed through the vitreous cutter is examined with regard to collagen moecular weigth	at time of surgery