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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05037981
Other study ID # vit105
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 10, 2015
Est. completion date August 20, 2021

Study information

Verified date September 2021
Source Cairo University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Vitiligo is a distressing disorder of depigmentation. In spite of multiple successful therapeutic regimens, disease relapse remains a challenge to patients and physicians. Most guidelines consider systemic treatments only in rapidly progressive disease with wider surface areas. This delay in halting the immune attack, may give the chance for further disease progression as well as establishment of resident memory T cell population predisposing to future disease relapses. The aim of this study was to assess the ability of early systemic therapy of localized (<2% BSA), recent onset (<6 months) vitiligo to control disease activity and minimize the possibility of recurrence.


Recruitment information / eligibility

Status Completed
Enrollment 25
Est. completion date August 20, 2021
Est. primary completion date August 10, 2021
Accepts healthy volunteers No
Gender All
Age group 6 Years to 60 Years
Eligibility Inclusion Criteria: - Patients = 6 years old of both genders - Early onset vitiligo (?6m duration) - Body surface area (BSA) affected =2% Exclusion Criteria: - Patients who received any previous treatment for vitiligo - Pregnant and lactating females - Patients with other cutaneous or systemic autoimmune diseases - Patients with contraindication to systemic corticosteroids

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Cairo University

Outcome

Type Measure Description Time frame Safety issue
Primary Duration needed to arrest of vitiligo activity Time needed for vitiligo patients to stop developing new lesions of vitiligo 6 months
Primary Duration of maintaining vitiligo stability Time before any new vitiligo lesions reappear 5 years
See also
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