VITILIGO Clinical Trial
Official title:
Response to Tregs in Innate Immunity Receptor LRP1 (CD91) and Tregs in Periferic Blood Mononuclear Cells in Patients With Non-segmentary Vitiligo
This study aims to evaluate some differences in the immune system between patients with
vitiligo and patients without the disease.
These differences will be evaluated by the extraction of peripheral blood that will be
analyzed before the treatment and after the treatment that, in the habitual way and at the
discretion of the responsible dermatologist.
Patients agreeing to participate in the study will be subjected to extraction of two tubes
(20 ml) of peripheral blood (baseline) and after 12 weeks (+/- 5 days) of treatment.
Therefore, neither treatment nor follow-up visits will be modified by participation, but will
be the same whether or not participate in the study.
In the case of controls, two peripheral blood tubes (20ml) will be removed in a single
participation.
Patients with vitiligo will also be asked to complete questionnaires to measure stress,
depression and perception of disease (PSS-10, Skindex-29, HADS, Likert) before and after 12
weeks (+/- 5 days) of therapeutic intervention .
This study will include 20 patients with active non-segmental vitiligo and 10 controls
without the disease. The duration of participation in this study will be 12 weeks (+/- 5
days) for patients with vitiligo and a single participation (extraction of 20 ml of
peripheral venous blood) for the controls.
n/a
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