Corneal Nerve Structure in Sjogren's

Status Completed

Clinical Trial Summary

Patients who are suspected of or diagnosed with Sjogren's disease will be evaluated for ocular symptoms and corneal nerve morphology. We are specifically interested in the relationship between Vitamin D level and aberrations in the morphology of the corneal nerves.

Clinical Trial Description

Patients with either suspected or confirmed diagnosis of Sjogren's disease will be recruited to participate. Participation will involve the completion of a brief survey (the OSDI), corneal evaluation with an aesthesiometer, corneal staining with fluorescein and lissamine green, and finally measurement of tear-film breakup time. In addition, participants will have their corneal nerve morphology evaluated with the Heidelberg confocal microscope and finally they will have a blood draw performed to assess vitamin D level. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03203382
Study type	Observational
Source	University of Pennsylvania
Contact
Status	Completed
Phase
Start date	September 2015
Completion date	April 2017

View Details

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