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Visual Acuity clinical trials

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NCT ID: NCT02659098 Completed - Clinical trials for Macular Degeneration

A Study to Evaluate the Safety and Clinical Response of Subretinal Administration of CNTO 2476 in Participants With Geographic Atrophy

PRELUDE
Start date: December 4, 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and performance profile of the suprachoroidal surgical approach and the Delivery System.

NCT ID: NCT02568254 Completed - Visual Acuity Clinical Trials

Evaluation of Three Daily Disposable Contact Lenses

Start date: September 3, 2015
Phase: N/A
Study type: Interventional

This is a single-site, 8-visit, double-masked, cross-over study involving three marketed products as study lenses. Participants will be randomly assigned each lens type, which will be worn for approximately two weeks (12 +/- 2 days) each. Participants will undergo a minimum washout period of 3 days before entering the study and undergo a minimum 7 day washout period between dispensing each lens type.

NCT ID: NCT02427477 Completed - Visual Acuity Clinical Trials

A Comparison of Two Daily Disposable Soft Contact Lenses

Start date: March 2015
Phase: N/A
Study type: Interventional

Approximately 120 subjects will be comparing two soft contact lenses for one week each.

NCT ID: NCT02409641 Completed - Visual Acuity Clinical Trials

A Pilot Study Investigating the Impact of Different IOL Designs on Subjective 2D and 3D Image Quality

Start date: February 2015
Phase: N/A
Study type: Interventional

The WHO, states that age related cataracts account for 51 percent of worldwide blindness and affect about 20 million people. Surgery with intraocular lens (IOL) implantation is the first line treatment for cataracts, thus there is an on going effort to improve IOL design and performance. It is planned to compare three different IOL designs in a psychophysical test setting. Most IOL testing is done in 2D scenarios such as Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity or contrast sensitivity testing. The use of 3D scenario would allow testing a more real-life situation. As various downsides of different IOL designs have been reported, testing of IOLs before surgical implantation is a promising approach to maximise patient satisfaction. Known deficiencies include amongst others reduced contrast sensitivity or light intensity. To test three different IOL designs, it is planned to have 2D healthy young subjects look through a stable, table mounted spectacle frame, in which the different IOLs can be inserted. This allows for subjective testing of IOL's in a 2D and 3D scenario.

NCT ID: NCT02394808 Completed - Visual Acuity Clinical Trials

2-week Evaluation of Marketed Silicone Hydrogel Contact Lenses in Indian Population

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the clinical performance of two marketed silicone hydrogel contact lenses in an Indian population in the following areas: physiological characteristics, comfort characteristics and vision characteristics.

NCT ID: NCT02365298 Completed - Visual Acuity Clinical Trials

Clinical and Laboratory Study of Lysozyme Deposition on Daily Disposable Contact Lenses

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

In vitro studies show that some hydrogel materials uptake more lysozyme than other hydrogel materials and that this protein remains largely active and promotes reduced cytokine response in an in vitro culture of human corneal epithelial cells. This study investigates whether these data transfer to the in vivo situation.

NCT ID: NCT02349438 Completed - Visual Acuity Clinical Trials

Assessment of Contact Lens Wettability Using Wavefront Aberrometry

Start date: December 2014
Phase: N/A
Study type: Interventional

This study will test the feasibility that differences in contact lens wettability can be measured with a wavefront sensor.

NCT ID: NCT02345720 Completed - Visual Acuity Clinical Trials

Effects of Multifocal Contact Lens on Ocular Tissue

Start date: December 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the etafilcon - PVP (multi-focal)

NCT ID: NCT01951703 Completed - Visual Acuity Clinical Trials

Senofilcon A Investigational Manufacturing Process

Start date: September 2013
Phase: N/A
Study type: Interventional

To evaluate the impact of a new contact lens hydration process

NCT ID: NCT01945892 Completed - Macular Edema Clinical Trials

Dexamethasone-Implant for the Treatment of Macula Edema Due to Irvine Gass Syndrome

Start date: November 2011
Phase: N/A
Study type: Observational

To analyze macula edema formation after cataract surgery called Irvine-Gass-Syndrome.