Vision Clinical Trial
Official title:
Eye Movements, Visual Perception and Attention
During visual fixation, small eye movements of which we are usually not aware, prevent the maintenance of a steady direction of gaze. These eye movements are finely controlled and shift retinal projection of objects within the fovea, the region of the retina where visual acuity is highest. This program of research examines the link between these eye movements and attention, and tests the hypothesis that attention, similarly to eye movements, can be controlled at the foveal level. Psychophysical experiments with human subjects, using state-of-the-art techniques, high resolution eyetracking and retinal stabilization are conducted to address these questions. Gaze-contingent calibration procedures are employed to achieve high accuracy in gaze localization. A custom developed gaze-contingent display is used to shift in real-time visual stimuli on the monitor to compensate for the observer eye movements during fixation periods and to maintain stimuli at a desired location on the retina. Experiments involve visual discrimination/detection tasks with stimuli presented at selected eccentricities within the fovea. Participants' performance and reaction times are examined under different conditions, in which various types of attention are manipulated. In addition to advancing our basic understanding of visual perception, this research leads to a better understanding of attentional control at the foveal scale and of the contribution of microscopic eye movements to the acquisition and processing of visual details.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | February 1, 2024 |
Est. primary completion date | February 1, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Subjects will be eligible for the study if they: - Are at least 18 years old - Speak English - Have read, understood, and signed the informed consent form Have normal visual acuity (20/20 or better) without correction (i.e. without glasses or contact lenses) and no known visual deficits. A standard visual acuity screening will be performed by means of a Snellen chart (the standard eye chart) at the beginning and the end of the experiments. Exclusion Criteria: - Subjects will be excluded if they: - Are under 18 years old - Cannot understand the experimental procedures Have reported vision loss, including the need for correction (i.e. glasses or contact lenses), or fail the visual acuity screening performed during the experiments. We expect a very minor portion of subjects to be excluded as a result of this test, as the good vision requirement will be clearly stated in our recruitment materials. There will be no data collection for subjects who will not pass the acuity test. |
Country | Name | City | State |
---|---|---|---|
United States | University of Rochester | Rochester | New York |
Lead Sponsor | Collaborator |
---|---|
University of Rochester | National Eye Institute (NEI) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Average Performance in Visual tasks | Proportion correct responses in visual tasks | Day 0 | |
Secondary | Microsaccades rate | Average number of microsaccades per second | Day 0 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05419713 -
Intermediate Visual Space Perception
|
N/A | |
Completed |
NCT00713076 -
Wettability of Contact Lenses With a Multi-Purpose Solution
|
N/A | |
Completed |
NCT04065061 -
Erinacine A-enriched Hericium Erinaceus Mycelia for Improvement of Recognition, Vision, and Functional MRI Alterations
|
N/A | |
Withdrawn |
NCT00886249 -
Depth of Focus Comparison Between Acrysof IQ and Acrysof Natural IOLs
|
||
Completed |
NCT00591110 -
Project inCharge: Increasing the Rate of Comprehensive Eye Care Utilization by Older African Americans Through Community-Based Eye Health Education Program
|
N/A | |
Completed |
NCT02033200 -
Safety Study Looking at the Effects of Stendra on Vision
|
Phase 4 | |
Withdrawn |
NCT01062672 -
Functional Neuroimaging of Cortical Plasticity in the Human Visual System
|
||
Completed |
NCT01138228 -
Does the VTS1000 Infra Red Vein Imager Allow Better Identification of Veins Than Normal Eyesight?
|
N/A | |
Completed |
NCT01057966 -
Bioavailability of Nutrients Contained in Softgel Capsules vs Tablets
|
Phase 4 | |
Recruiting |
NCT00768586 -
Analysis of the Early Development of the Visual Function in Extreme Premature Infants Under 28th Weeks of Gestation
|
N/A | |
Completed |
NCT00357409 -
GABA Levels in the Brains of Blind People
|
N/A | |
Completed |
NCT05533658 -
The Effects of VisionPureâ„¢ on Indices of Vision Health and Cognitive Function
|
N/A | |
Recruiting |
NCT04332783 -
Isolating and Mitigating Sequentially Dependent Perceptual Errors in Clinical Visual Search
|
N/A |