The Effects of Butyrate Enemas on Visceral Perception

Visceral (Hyper)Sensitivity Clinical Trial

Official title:

The Effects of Butyrate Enemas on Visceral Perception

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00726817
• Other study ID #: MEC 06-3-020
• Status: Completed
• Phase: N/A
• First received: July 29, 2008
• Last updated: February 22, 2017
• Start date: December 2007

Study information

• Verified date: July 2008
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

During this double blind, placebo controlled, randomised cross over study, healthy volunteers received an enema once daily for one week containing either placebo (saline), 50mM butyrate or 100mM of butyrate. Before and directly after each test period a barostat protocol was performed to measure parameters for visceral perception.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. primary completion date: February 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• healthy

Exclusion Criteria:

• age, under 18 or over 65

• use of pre- or probiotics during study and 3 months previous to study

• previous bowel complaints

• gastrointestinal disease or abdominal surgery

Related Conditions & MeSH terms

• Visceral (Hyper)Sensitivity

Intervention

Drug:
• Butyrate

Locations

Country	Name	City	State
Netherlands	Maastricht University	Maastricht	Limburg

Sponsors (1)

Lead Sponsor	Collaborator
Maastricht University Medical Center

Country where clinical trial is conducted

Netherlands,