Laryngoscopy and Coronary Artery Bypass Graft Surgery

Videolaryngoscopy Clinical Trial

— VL  

Official title:

Hemodynamic Response to Various Laryngoscopes During Tracheal Intubation in CABG Patients

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06349005
• Other study ID #: 111
• Status: Not yet recruiting
• Phase: N/A
• Start date: April 10, 2024
• Est. completion date: September 1, 2024

Study information

• Verified date: March 2024
• Source: Konya Meram State Hospital
• Contact: Betul Kozanhan, M.D.
• Phone: (0332) 310 50 00
• Email: betulkozanhan[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this prospective, randomized, controlled trial, the purpose is to compare Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope in terms of hemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

Description:

During endotracheal intubation, laryngoscopy can significantly affect hemodynamic responses, including tachycardia and elevated blood pressure, which may be particularly detrimental to individuals with cardiovascular conditions. Various studies have explored the hemodynamic reactions associated with laryngeal stimulation through different intubation devices. Researchers hypothesize that endotracheal intubation using video laryngoscopy will elicit a reduced hemodynamic response compared to traditional (Macintosh) laryngoscopy. In this prospective and randomized clinical study, the purpose is to compare the Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope concerning haemodynamic response associated with intubation in adult patients undergoing Coronary Artery Bypass Surgery (CABG).

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 112
• Est. completion date: September 1, 2024
• Est. primary completion date: August 1, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Age range between 18 and 75 years.
• Scheduled for elective coronary artery bypass surgery.
• Classified under American Society of Anesthesiologists (ASA) physical status II-III.
• Patients with no history of difficult intubation or associated risk factors.

Exclusion Criteria:

• Emergency case
• Predicted difficult airways
• Body mass index > 35 kilograms per meter squared
• Baseline hemodynamic instability

Related Conditions & MeSH terms

• Videolaryngoscopy

Intervention

Other:
• Tracheal intubation using Storz VL
Video-assisted intubation technique using Storz VL
• Tracheal intubation using Macintosh laryngoscopy
Traditional intubation technique using Macintosh laryngoscopy
• Tracheal intubation using MacGrath VL
Video-assisted intubation technique using MacGrath VL
• Tracheal intubation using EzVision VL
Video-assisted intubation technique using EzVision VL

Locations

Country	Name	City	State
Turkey	Betul Kozanhan	Konya

Sponsors (1)

Lead Sponsor	Collaborator
Konya Meram State Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Hemodynamic response	Change from baseline invasive blood pressure	Change from baseline Systolic or Diastolic or mean Blood Pressure at 10 minutes
Primary	Hemodynamic response	Change from baseline heart rate	Change from baseline heart rate at 10 minutes
Secondary	Intubation time	The duration from when the laryngoscope passes through the teeth until it is withdrawn back to the teeth will be measured.	180 seconds
Secondary	Visualization of the glottis	According to Cormack Lehane classification four grades (1-4). The higher the grade, the higher the likelihood of difficult intubation.	180 seconds