Vestibular Abnormality Clinical Trial
Official title:
Test-Retest Reliability of oVEMP's Across Different Electrode Montages
Verified date | March 2018 |
Source | Vanderbilt University Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
"Test-Retest Reliability of ocular vestibular evoked myogenic potentials (oVEMPs) across
different electrode montages."
The purpose of this project is to compare the response characteristics of the ocular
vestibular evoked myogenic potential in patients grouped by decade (i.e. 20's-90's) using two
different recording montages and two different stimulus types (i.e. air and bone conducted
sound). The long-term goal is to increase the sensitivity and specificity of the oVEMP when
used clinically to identify vestibular disorders affecting the utricle and superior portion
of the vestibular nerve.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | May 2018 |
Est. primary completion date | April 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 99 Years |
Eligibility |
Inclusion Criteria: - Normal hearing and no history of balance disorders Exclusion Criteria: - Hearing loss, a large amount of ear wax, inner ear of balance problems, and/or no recordable eye muscle responses |
Country | Name | City | State |
---|---|---|---|
United States | Vanderbilt University Medical Center | Nashville | Tennessee |
Lead Sponsor | Collaborator |
---|---|
Vanderbilt University Medical Center |
United States,
Chang CM, Cheng PW, Wang SJ, Young YH. Effects of repetition rate of bone-conducted vibration on ocular and cervical vestibular-evoked myogenic potentials. Clin Neurophysiol. 2010 Dec;121(12):2121-7. doi: 10.1016/j.clinph.2010.05.013. Epub 2010 Jun 11. — View Citation
Chihara Y, Iwasaki S, Ushio M, Murofushi T. Vestibular-evoked extraocular potentials by air-conducted sound: another clinical test for vestibular function. Clin Neurophysiol. 2007 Dec;118(12):2745-51. Epub 2007 Oct 1. — View Citation
Curthoys IS, Iwasaki S, Chihara Y, Ushio M, McGarvie LA, Burgess AM. The ocular vestibular-evoked myogenic potential to air-conducted sound; probable superior vestibular nerve origin. Clin Neurophysiol. 2011 Mar;122(3):611-6. doi: 10.1016/j.clinph.2010.07 — View Citation
Govender S, Rosengren SM, Colebatch JG. The effect of gaze direction on the ocular vestibular evoked myogenic potential produced by air-conducted sound. Clin Neurophysiol. 2009 Jul;120(7):1386-91. doi: 10.1016/j.clinph.2009.04.017. Epub 2009 May 22. — View Citation
Kantner C, Gürkov R. Characteristics and clinical applications of ocular vestibular evoked myogenic potentials. Hear Res. 2012 Dec;294(1-2):55-63. doi: 10.1016/j.heares.2012.10.008. Epub 2012 Oct 30. Review. — View Citation
Makowiec K, McCaslin DL, Jacobson GP, Hatton K, Lee J. Effect of Electrode Montage and Head Position on Air-Conducted Ocular Vestibular Evoked Myogenic Potential. Am J Audiol. 2017 Jun 13;26(2):180-188. doi: 10.1044/2017_AJA-16-0108. — View Citation
Murnane OD, Akin FW, Kelly KJ, Byrd S. Effects of stimulus and recording parameters on the air conduction ocular vestibular evoked myogenic potential. J Am Acad Audiol. 2011 Jul-Aug;22(7):469-80. doi: 10.3766/jaaa.22.7.7. — View Citation
Nguyen KD, Welgampola MS, Carey JP. Test-retest reliability and age-related characteristics of the ocular and cervical vestibular evoked myogenic potential tests. Otol Neurotol. 2010 Jul;31(5):793-802. doi: 10.1097/MAO.0b013e3181e3d60e. — View Citation
Piker EG, Jacobson GP, Burkard RF, McCaslin DL, Hood LJ. Effects of age on the tuning of the cVEMP and oVEMP. Ear Hear. 2013 Nov-Dec;34(6):e65-73. doi: 10.1097/AUD.0b013e31828fc9f2. — View Citation
Piker EG, Jacobson GP, McCaslin DL, Hood LJ. Normal characteristics of the ocular vestibular evoked myogenic potential. J Am Acad Audiol. 2011 Apr;22(4):222-30. doi: 10.3766/jaaa.22.4.5. — View Citation
Rosengren SM, McAngus Todd NP, Colebatch JG. Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound. Clin Neurophysiol. 2005 Aug;116(8):1938-48. — View Citation
Sandhu JS, George SR, Rea PA. The effect of electrode positioning on the ocular vestibular evoked myogenic potential to air-conducted sound. Clin Neurophysiol. 2013 Jun;124(6):1232-6. doi: 10.1016/j.clinph.2012.11.019. Epub 2013 Jan 18. — View Citation
Todd NP, Rosengren SM, Aw ST, Colebatch JG. Ocular vestibular evoked myogenic potentials (OVEMPs) produced by air- and bone-conducted sound. Clin Neurophysiol. 2007 Feb;118(2):381-90. Epub 2006 Dec 1. — View Citation
Welgampola MS, Carey JP. Waiting for the evidence: VEMP testing and the ability to differentiate utricular versus saccular function. Otolaryngol Head Neck Surg. 2010 Aug;143(2):281-3. doi: 10.1016/j.otohns.2010.05.024. — View Citation
* Note: There are 14 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Development of Normative Values per Decade | The oVEMP N1-P1 amplitude and N1 latency will be measured for each subject and will be used to calculate normative values for each decade. The goal is to provide clinics with normative information to base clinical evaluations on. | 5 months for data collection, one visit per subject. |
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