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Vertigo clinical trials

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NCT ID: NCT05960786 Completed - Vertigo Clinical Trials

Treating the Symptoms of Vertigo in a Real-world Setting Using the OtoBand

Start date: February 2, 2023
Phase: N/A
Study type: Interventional

The goal of this virtual clinical trial is to determine the effectiveness of two study devices in providing temporary relief to adults aged 18-70 who suffer from symptoms of chronic vertigo. The main question[s] it aims to answer are: - Which device do participants respond better to (that is, find more relief)? - To what degree do participants find relief? Participants will be: - Enrolled up to 49 days; 14 days in Baseline Phase (no device) and 21 days in Treatment Phase (study device) for Study Arm 1 or 28 days in Treatment Phase (study device) for Study Arm 2 - Randomized and stratified into groups based on diagnosis to be assigned a study device - Asked to use the study device as instructed by the study coordinator - Asked to download a study app to submit daily diaries regarding their symptoms and use of device, and to participate in tele-health visits with study coordinators - Asked to provide their vertigo diagnosis from their physician - Compensated for their participation Researchers will compare the randomized groups to see which groups respond better to which device.

NCT ID: NCT05944159 Completed - Clinical trials for Temporomandibular Joint Disorders

Temporomandibular Joint and Soft Tissue Mobilisation Techniques on Bening Paroxymal Vertigo

Start date: July 7, 2022
Phase: N/A
Study type: Interventional

The purpose of this study was to investigated effectiveness of temporamandibular joint and soft tissue mobilization on patients with Benign Paroxysmal Positional Vertigo (BPPV).

NCT ID: NCT05922774 Recruiting - Clinical trials for Benign Paroxysmal Positional Vertigo

Cervical Vestibular Evoked Myogenic Potentials in Recurrent and Persistant Benign Paroxysmal Positional Vertigo

Start date: June 19, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to compare the cervical vestibular evoked myogenic potentials in recurrent/persistant BPPV and nonrecurrent BPPV. Recurrent/persistant BPPV is considered as the patients who require more than one repositioning manuever for the resolution of symptoms and the recurrent cases in the first three months after the diagnosis. The main question[s] it aims to answer are: - Is there any difference between the cVEMP findings of diseased ears of recurrent and nonrecurrent BPPV cases? - Is there any difference between the cVEMP findings of diseased ears and healthy ears of BPPV patients - Is there any difference between the cVEMP findings of healthy ears of recurrent and nonrecurrent BPPV cases and healthy controls? Patients with VNG confirmed BPPV will be recruited and CVEMP test will be performed before the therapeutic manuevers. Control visits will be scheduled on the 7th day after the therateutic menuevers are performed. Patients will be followed-up for 4 weeks after the resolution of symptoms. Researchers will compare recurrent (Group 1), nonrecurrent (group 2) BPPV patients and healthy controls (Group 3) to see if there is any difference between the cVEMP findings of two groups.

NCT ID: NCT05897853 Completed - Vertigo Clinical Trials

Impact of Vertigoheel® on Patients Suffering From Bilateral Vestibulopathy and Functional Dizziness

HealVertigo
Start date: November 29, 2021
Phase:
Study type: Observational

In this study the researcher observe how vertigo symptoms change during two months of treatment with the natural medicinal product Vertigoheel©. Adult patients suffering from vertigo symptoms can participate if they are diagnosed with bilateral vestibulopathy (BVP) or functional dizziness (FD) and assigned to Vertigoheel treatment. Participating patients receive an examination at study start and after 2 months of Vertigoheel treatment. The study focuses on patient reported outcomes assessed by questionnaires. Vertigo symptoms are assessed by the Dizziness Handicap Inventory questionnaire. Patients' quality of life is assessed by a questionnaire. Body sway is assessed by static posturography. FD patients are additionally tested for depressive and anxiety symptoms by questionnaires. BVP patients are additionally tested for vestibular function by video head impulse test and caloric testing. Adverse events and other observations related to safety (physical examination and vital signs) are evaluated. Vertigo is a common symptom with significant adverse effects on patients' quality of life. Regardless of the exact cause of vertigo attacks, it is important to reduce the frequency, intensity, and duration of vertigo attacks with an effective medication that has no or minimal adverse effect. Vertigoheel®, a natural medicinal product consisting of four ponderable active ingredients, is approved in Germany as treatment for vertigo of various origins. However, no systematic data are available for Vertigoheel® regarding patient-reported outcomes in BVP and FD as the most accepted endpoint in vertigo studies.

NCT ID: NCT05889676 Recruiting - Vertigo Clinical Trials

Validation of a Simultaneous Ocular/Cervical VEMP With Mastoid Vibration by B250

BCVEMP By B250
Start date: May 30, 2023
Phase:
Study type: Observational [Patient Registry]

A Validation study in which the standard separate cVEMP and oVEMP will be compared with a new protocol in which the cVEMP and oVEMP can be recorded simultaneously in response to a mastoid vibration by bone transducer B250

NCT ID: NCT05863949 Not yet recruiting - Clinical trials for Vitamin D Deficiency

Clinical Trial of Vit D and Calcium for Recurrent BPPV

Start date: July 2023
Phase: N/A
Study type: Interventional

Randomized double blind placebo controlled trial of vitamin D supplements, with or without calcium supplementation, versus placebo in reduction of recurrences in BPPV.

NCT ID: NCT05853328 Completed - BPPV Clinical Trials

Comparison of EM and SM+ Maneuvers in Patients With BPPV

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Objective of this prospective randomized treatment trial is to compare the effectiveness of the SemontPLUS (SM+) with the Epley maneuver (EM) for the therapy of posterior canal benign paroxysmal positional vertigo canalolithiasis (pcBPPV).

NCT ID: NCT05851508 Recruiting - Meniere Disease Clinical Trials

The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease

PREDMEN
Start date: October 1, 2023
Phase: Phase 3
Study type: Interventional

Ménière's disease is an inner ear disorder in which patients suffer from attacks of vertigo, tinnitus and hearing loss. To date, it is unclear what the best treatment for this condition is. Giving injections in the inner ear with the adrenal cortical hormone methylprednisolone is a treatment that is already widely used, but still there is insufficient evidence in the effectiveness of this treatment. This multicenter trial compares a patient group which receives injections of methylprednisolone to a patient group which receives placebo injections. Subsequently, dizziness, tinnitus, hearing loss and quality of life will be assed and compared for the above mentioned groups, over a period of one year.

NCT ID: NCT05846711 Recruiting - Vertigo Clinical Trials

The Accuracy of Manual BPPV Diagnostics When Using VNG Goggles.

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The aim is to investigate the accuracy of manual diagnostics of benign paroxysmal positional vertigo (BPPV) by comparing it to BPPV diagnostics in mechanical rotational chair (TRV chair). VNG (videonystagmography) goggles will be used in both scenarios. Furthermore, the investigators will examine the importance of angulation and velocity in relation to the diagnostic outcome.

NCT ID: NCT05834452 Recruiting - Clinical trials for Benign Paroxysmal Positional Vertigo

Treatment of Posterior Benign Paroxysmal Positional Vertigo With Mechanical Rotational Chair.

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Comparison of treatment efficacy of Epley maneuver and 360 maneuver in a mechanical rotational chair (TRV chair) in patient with posterior benign paroxysmal positional vertigo (BPPV).