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Cardiac RadiothErapy for VEntricular Tachycardia — CREVET  

Ventricular Tachycardia Clinical Trial

Official title:
Cardiac RadiothErapy for VEntricular Tachycardia

Clinical Trial Summary

Objective: To explore in our center the feasibility and safety of a SBRT treatment method for VT. Study population: Patients with ventricular tachycardia that are refractory to dose-escalated antiarrhythmic drugs and where catheter ablation has either already been performed or is deemed to be unsuccessful or associated with high risks. Intervention: Patients will be treated with a stereotactic body radiotherapy technique as a single fraction treatment up to a dose of 25 Gy delivered to the VT substrate defined by electrophysiological mapping. Main study endpoints: The primary aim is to explore the feasibility and safety of a SBRT treatment method for refractory VT. Secondary endpoints include an assessment of the efficacy of the treatment, quality of life, late toxicity and overall survival. Patients will have to fill in a quality-of-life questionnaire before and after the radiotherapy treatment. The risk associated with this trial is an increase in toxicity.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05973578
Study type Interventional
Source Universitaire Ziekenhuizen KU Leuven
Contact Patrick Berkovic, MD, PhD
Phone +32-16-34-51-15
Email Patrick.berkovic@uzleuven.be
Status Recruiting
Phase N/A
Start date May 23, 2023
Completion date May 1, 2026
View Details
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