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Dose Escalation for SBRT of Recurrent VT Ventricular Tachyarrhythmia - a Single Center, Phase II Clinical Trial — DEFT STAR  

Ventricular Tachycardia Clinical Trial

Official title:
Dose Escalation for Stereotactic Cardiac Radiation Therapy of Recurrent Ventricular Tachyarrhythmia - a Multi Center, Phase II Clinical Trial

Clinical Trial Summary

The objective of this study is to demonstrate that higher radiation doses are necessary to induce transmural scar formation which is currently assumed to be the underlying mechanism of successful long-term efficacy of VT treatment and therefore dose-escalation will lead to a significantly reduced long-term VT recurrence rate compared to the currently applied single dose of 25 Gy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05594368
Study type Interventional
Source University of Zurich
Contact Nicolaus Andratschke, MD
Phone 0041 44 255 4238
Email nicolaus.andratschke@usz.ch
Status Recruiting
Phase Phase 1
Start date July 1, 2022
Completion date June 30, 2025
View Details
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