Non-invasive Ablation of Ventricular Tachycardia

Status Completed

Clinical Trial Summary

Phase I/II study of 4-D Navigated Non-invasive radiosurgical ablation of ventricular tachycardia (NIRA-VT).

Clinical Trial Description

The goal of this project dealing with 4D-navigated substrate ablation is to evaluate the feasibility and safety of elimination of the scar-related monomorphic ventricular tachycardia (VT) or tachycardias by stereotactic radiosurgical ablation that is completely non-invasive. The arrhythmic substrate is defined as the scar after myocardial infarction (MI) described by transthoracic echocardiography (TTE) and specified by PET-CT or MRI. All sustained monomorphic VT induced by programmed ventricular stimulation via implanted ICD (Implantable Cardioverter Defibrillator) will be analyzed using body surface ECG mapping. The target volume for stereotactic radiosurgical ablation (single dose of 25 Gy) will be based on accordance between a post-infarction scar (PET-CT or MRI imaging) and arrhythmic substrate (body surface ECG mapping). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03601832
Study type	Interventional
Source	University Hospital Ostrava
Contact
Status	Completed
Phase	N/A
Start date	August 1, 2018
Completion date	January 31, 2020

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See also
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