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Renal Denervation In Patient Undergoing VT Ablation:Combined Renal Denervation and VT Ablation vs. Simply VT Ablation — ARDEVAT  

Ventricular Tachycardia Clinical Trial

Official title:
Renal Denervation In Patient Undergoing VT Ablation:Combined Renal Denervation and VT Ablation vs. Simply VT Ablation

Clinical Trial Summary

Study hypothesis: With optimal medical therapy and repeated ablations, an additional renal denervation may have protective effects in terms of vegetative intrinsic activity and lead to a significant reduction in VT Burdens. Study design: Multicenter, randomized, prospective, single-blind clinical trial.

Clinical Trial Description

Study protocol: Catheter ablation of ventricular tachycardia versus combined catheter ablation of ventricular tachycardia and renal denervation. A total of 50 patients with ventricular tachycardia treated with ICD shocks or ATP will be enrolled in this study. The randomization in the study is done before ablation. For the ablation, an arterial access is required in both groups. During a 30 minutes waiting time which will apply to both groups, renal denervation will be performed. In this period of time operators and staff will be blinded for the procedure, thereby they won't know if the patients will receive a renal denervation, in that way the investigators are avoiding a bias of future treatment of the patients. Follow up and repeat procedures: All Patients will be followed for a period of 3, 6, 9, 12 and 18 months after the procedure. Regular visits are done in the investigators office. The visit will include ICD Interrogation, VT documentation in ICD Holter, 24-hour Holter ECG or Tele-ECGs, echocardiography. Re- VT ablations are allowed at any time. In case of renal artery stenosis, denervation will not be performed. Drug therapy can be continued. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02071511
Study type Interventional
Source Universitätsklinikum Hamburg-Eppendorf
Contact
Status Terminated
Phase N/A
Start date January 2014
Completion date August 2016
View Details
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