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Clinical Trial Summary

This study will test the hypothesis that many human heart rhythm disorders are caused by small localized sources, where brief ablation may successfully eliminate the heart rhythm disorder.


Clinical Trial Description

The investigators will enroll patients with documented rapid heart rates from the bottom chambers of the heart (ventricular tachyarrhythmias).

During electrophysiological study, the investigators will map the localized sources of these heart rhythm disorders.

1. The 'active' group will prospectively receive brief ablation at localized sources (Focal Impulse and Rotor Modulation, FIRM).

2. The control group will be a historical cohort who have received traditional ablation for this disorder.

All patients will be followed for up to 1 year to ensure that they have no recurrent arrhythmias. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01492764
Study type Observational
Source University of California, San Diego
Contact
Status Completed
Phase
Start date June 2011
Completion date August 2014

See also
  Status Clinical Trial Phase
Withdrawn NCT05084391 - Phase I/II Randomized Study of Stereotactic Ablative Radiotherapy (SABR) Versus Standard of Care for Refractory Structural Cardiac Arrhythmias (SABR-HEART) Phase 1/Phase 2
Completed NCT01906775 - Sub-threshold Pacing to Prevent Pacemaker-induced Ventricular Tachycardia N/A
Completed NCT00853645 - Initial Chronic Human Validation Study: Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) System N/A