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Benefit of One Month Zopiclone Intake on Adaptative Servoventilation Compliance — ZODIAC  

Ventricular Dysfunction Clinical Trial

Official title:
Adaptative Servoventilation Compliance in Left Ventricular Dysfunction Patients With Central Sleep Apnea: Benefit of One Month Hypnotic (Zopiclone) Versus Placebo

Clinical Trial Summary

The study evaluate the effect of adaptative servoventilation (ASV) initiation combined with 14 days Zopiclone vs Placebo treatment in patients with central sleep apnea (CSA) syndrome.

Clinical Trial Description

ASV remain the optimal treatment for CSA in Heart Failure patients with preserved left ventricular ejection fraction (LVEF). Yet, the adaptation to the ventilation is extremely challenging and the resulting difficulties encountered to sleep induction might be a reason for dropping out. Zopiclone is indicated for the short-term treatment of insomnia where sleep initiation or sleep maintenance are prominent symptoms. In this study, Zopiclone, as sedative and hypnotic agent, is used during the ASV initiation period. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02820441
Study type Interventional
Source University Hospital, Grenoble
Contact
Status Terminated
Phase Phase 4
Start date May 2016
Completion date June 2018
View Details
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