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Ventral Hernia clinical trials

View clinical trials related to Ventral Hernia.

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NCT ID: NCT05488288 Recruiting - Ventral Hernia Clinical Trials

Bariatric SUrgery With Mesh REpair of Ventral Hernia: a Randomized Controlled Trial

BeSURE
Start date: July 24, 2023
Phase: Phase 3
Study type: Interventional

The primary objective of the study is to demonstrate that hernia recurrence (VH) repair with non absorbable mesh concomitant to Bariatric Surgery (BS) decreases the risk of VH, with or without surgical repair, during the first two years after BS when compared to VH suture repair without mesh. As secondary objectives, the study aims to assess the impact of concomitant VH repair with non absorbable mesh versus suture repair in morbidly obese BS candidates on the following measures: - hernia recurrence at 1 year after randomization; - reoperation for hernia recurrence at 2 years after randomization; - strangulated hernia, surgical infection and mesh bulging at one year after randomization; - postoperative morbidity and mortality at 90 days after randomization; - benefit-risk ratio; - chronic pain at three months, six months, one year and two years after randomization; - quality of life during the two years after randomization; - incremental cost utility ratio; - short- and mid-term weight loss. To study if the efficacy of mesh versus suture VH repair differs according to the type and size of VH and to the surgical technique.

NCT ID: NCT05472987 Recruiting - Ventral Hernia Clinical Trials

Robotic Versus Open Ventral Hernia Repair

ROVHR
Start date: July 25, 2022
Phase: N/A
Study type: Interventional

This is a randomized trial comparing open retromuscular ventral hernia repair to robotic retromuscular ventral hernia repair.

NCT ID: NCT05423574 Completed - Ventral Hernia Clinical Trials

Robotic Trans-Abdominal Retromuscular Umbilical Prosthesis (r-TARUP)

r-TARUP
Start date: January 1, 2021
Phase:
Study type: Observational

Combining the advantage of minimally invasive surgery with laparoscopy to reduce postoperative complications and the placement of a retromuscular prosthesis with closure of the defect in order to reduce the risk of adhesion and restore normal anatomy in the treatment of primary and incisional ventral hernias, is made possible through robotic assistance. The challenge of this study concerns the evaluation of quality of life, postoperative pain and recurrence at 6 months in the management of primary and incisional ventral hernias by robot-assisted laparoscopic approach.

NCT ID: NCT05388929 Recruiting - Inguinal Hernia Clinical Trials

Methocarbamol in Ventral and Inguinal HR

Start date: June 23, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to gather information on methocarbamol as a pain management treatment for ventral or inguinal hernia repair. Methocarbamol has been part of the pain management treatment for both inpatient and outpatient procedures at Prisma Health. This study will compare the outcomes of patients who receive methocarbamol, those who receive the standard opioid pain management treatment, and those who receive methocarbamol plus the standard opioid pain management treatment. Participants will be randomized into one of the study groups listed below. Primary ventral hernia repair or inguinal hernia repair: Group 1: standard opioid after surgery Group 2: methocarbamol after surgery Open or robotic ventral hernia repair outpatient: Group 1: standard opioid after surgery Group 2: standard opioid plus methocarbamol after surgery Open or robotic ventral hernia repair inpatient: Group 1: standard opioid at discharge Group 2: standard opioid plus methocarbamol at discharge A total of 200 participants will be included in the study. Participation will last for about 30 days after surgery.

NCT ID: NCT05374096 Completed - Anxiety Clinical Trials

Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery

Start date: June 13, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether listening to music during surgery has an effect on pain or anxiety after surgery.

NCT ID: NCT05177991 Recruiting - Inguinal Hernia Clinical Trials

Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Start date: March 1, 2022
Phase: Early Phase 1
Study type: Interventional

While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective, randomized trial comparing the postoperative pain control in minimally invasive ventral and inguinal hernia repair patients who receive an Exaparel-based TAP block compared to the traditional bupivacaine (Marcaine) TAP block.

NCT ID: NCT05142618 Recruiting - Ventral Hernia Clinical Trials

Pilot Trial of Abdominal Core Rehabilitation To Improve Outcomes After Ventral Hernia Repair

ABVENTURE-P
Start date: April 19, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the potential role of physical therapy in improving outcomes after ventral hernia repair.

NCT ID: NCT05093894 Withdrawn - Ventral Hernia Clinical Trials

Microlyte in Prevention of SSI After Open Ventral Hernia Repair

Start date: December 14, 2021
Phase: N/A
Study type: Interventional

Participants who are scheduled to have open ventral hernia repair (OVHR) will be asked to take part in this study. The purpose of this study is to find out if placing Microlyte (which is a dissolvable sheet coated in silver) on the surgical incision is better than placing nothing on the surgical incision when it comes to decreasing the chance of surgical site infections. The study device has been cleared by the Food and Drug Administration (FDA) for use on surgical incisions. A total of 280 participants will be included in the study. Participation will last for about 90 days.

NCT ID: NCT04986917 Recruiting - Ventral Hernia Clinical Trials

Laparoscopic Ventral Hernia Repair With Routine Defect Closure Using Su2ura® Approximation Device

Start date: January 19, 2022
Phase: N/A
Study type: Interventional

Study includes 5 visits: Screening, Baseline/Surgery, and 14 days, 3 months, 12months Follow-Ups post-surgery. The actual point of enrollment for each subject is considered the day of surgery. Total study duration is up to 12 months post-surgery. Surgery will be performed under general anesthesia. Standard antibiotic prophylaxis will be administered 30 min prior to skin incision. A surgical assistant will be selected by the PI from the surgical staff of the department. The procedure will involve placement of laparoscopic ports, reduction of the hernia sac, closure of the defect with the Su2ura® approximation device and fixation of mesh with tacks over the closed defect in an IPOM fashion. Based on surgeon consideration, primary umbilical hernia defects under 2 cm will be repaired with or without mesh. Study follow-up visits will take place 14 days, 3 months and 12 months post-surgery.

NCT ID: NCT04947202 Completed - Ventral Hernia Clinical Trials

Clinical Study on the Safety of SAFIL® MESH

SAFIL_MESH
Start date: July 1, 2021
Phase:
Study type: Observational

Observational, Retrospective, Multi-center Clinical Study on the Safety of SAFIL® MESH in Patients Undergoing Reinforcement of Soft Tissues After Abdominal Wall Surgery or Other Fascial Defects