Ventilator Weaning Clinical Trial
Official title:
Automatic Control of Pressure Support Ventilation in Surgical Intensive Care Units - a Bicentric, Prospective, Randomized, Controlled Trial
This bicentric, randomized, controlled trial examines the effectiveness of an automatic control of pressure support ventilation (SmartCare/PS) in critically ill patients.
During the weaning process vigilance, pulmonary mechanics and respiratory drive of the patient are changing. Consequently, ventilation settings have to be modified very often. The modifications can be conducted either according to a weaning protocol or automatically by an expert system (SmartCare/PS). This trial compares protocol-guided weaning with automatic weaning in post-surgical patients and examines the effect on total ventilation time, numbers of manipulations and alarms of the ventilator, length of stay in the ICU and in the hospital, 28- and 90-day mortality. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02894177 -
Transcutaneous Carbon Dioxide Pressure (tcPCO2) Monitoring for the Prediction of Extubation Failure in the ICU
|
N/A | |
Recruiting |
NCT05114551 -
ICU Predictive Score of WEaning Success in Patients At Risk of Extubation Failure
|
||
Completed |
NCT04011852 -
The Role of Chest Electrical Impedance Tomography in the Pediatric Ventilator Weaning
|
||
Recruiting |
NCT02921334 -
Early Tracheotomy for Switching Between Invasive and Noninvasive Ventilation to Facilitate Weaning
|
N/A | |
Recruiting |
NCT02921347 -
Switching Between Invasive and Noninvasive Ventilation to Facilitate Weaning in Difficult-weaning Patients
|
N/A | |
Recruiting |
NCT06055413 -
Home-based Optimization of Mechanical Ventilation in Children
|
N/A | |
Active, not recruiting |
NCT04023643 -
Pediatric Ventilation Weaning
|
N/A | |
Completed |
NCT05254691 -
WOB and Paediatric Mechanical Ventilation
|
N/A | |
Recruiting |
NCT05999526 -
Mechanical Ventilation Reconnection for One Hour After Spontaneous Breathing Trial
|
N/A | |
Active, not recruiting |
NCT02820090 -
The Predictive Effect of the Inflammatory Response on the Evacuation of Mechanical Ventilation and the Mechanism
|
N/A | |
Recruiting |
NCT01131377 -
Acetazolamide Facilitates Ventilator Weaning
|
N/A | |
Completed |
NCT02412202 -
Echocardiographic Detection of Extravascular Lung Water Increase During Weaning From Mechanical Ventilation
|
N/A | |
Recruiting |
NCT05380687 -
Time Course of Neuro-ventilatory Efficiency During a Spontaneous Breathing Training
|
N/A | |
Terminated |
NCT01535755 -
A Protocol to Wean From Noninvasive Mechanical Ventilation
|
N/A | |
Completed |
NCT04711759 -
Physiologic Effects of High-flow Nasal Cannula Versus Standard Oxygen Therapy Postextubation in Critically Ill Patients
|
N/A | |
Completed |
NCT03433105 -
Oxygen Uptake in Weaning of Patients From Prolonged Mechanical Ventilation
|
||
Completed |
NCT00505804 -
A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium
|
Phase 2 | |
Completed |
NCT02946502 -
Handgrip Strength Value in Predicting Mechanical Ventilation Weaning
|
N/A | |
Completed |
NCT03673683 -
Sedation and Weaning in Children Requiring Invasive Mechanical Ventilation
|
N/A | |
Terminated |
NCT03019107 -
Breath Synchronized Abdominal Muscle Stimulation to Facilitate Ventilator Weaning: a Pilot Study
|