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Ventilator Lung clinical trials

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NCT ID: NCT06449924 Not yet recruiting - Pediatric ALL Clinical Trials

An Endotracheal Tube Inserted to the Level of the Hypopharynx

Start date: June 10, 2024
Phase:
Study type: Observational

The goal of this observational study is to assess the incidence of successful ventilation using an ETT inserted orally above the vocal cords in pediatric patients undergoing surgeries. The main question it aims to answer are: Is the use of an endotracheal tube (ETT), positioned in the hypopharynx with its tip placed just above the vocal cords an easy, safe and effective way for the ventilation of pediatric patients who are undergoing surgery under general anesthesia via orotracheal intubation? The procedures to be performed in this study are standard of care. They are also used by pediatric anesthesiologists in the oral intubation of pediatric patients suffering from tumor or abscess.

NCT ID: NCT06370507 Not yet recruiting - Surgery Clinical Trials

Monitoring of Lung Ventilation Through Electrical Impedance Tomography During Pediatric Surgery

VentiPed
Start date: April 15, 2024
Phase:
Study type: Observational [Patient Registry]

Given the scarcity of studies aimed at assessing the effect of anesthesia and m ventilation on the distribution of lung ventilation in pediatric patients undergoing surgery, with the exclusion of thoracic surgery, the present prospective observational study would shed the light on ventilation practice in pediatric anesthesia for surgery. This study wold fill the actual gap allowing the evaluation, through electrical impedance tomography (EIT) of the distribution of lung ventilation across the different phases of anesthesia for pediatric surgery. These insights could contribute to improve clinical practice and research in the management of ventilation in pediatric patients undergoing anesthesia for surgery.

NCT ID: NCT06296277 Not yet recruiting - Surgery Clinical Trials

Mechanical Ventilation in Surgical Patients

MEET VENUS
Start date: June 1, 2024
Phase:
Study type: Observational

This is an investigator-initiated, international, multicenter, prospective, cross-sectional study that aims to 1) describe the incidence and types of postoperative pulmonary complications (PPCs), 2) describe patient demographics, baseline characteristics, and intraoperative ventilation management, 3) describe the occurrence of intraoperative adverse events (IAEs), and 4) their associations with PPCs, 5) assess the practice of intraoperative mechanical ventilation. Patients will be eligible for participation if: 1) adult and 2) receiving intraoperative ventilation during general anesthesia for surgery. Patients receiving ventilation outside of an operating room as well as patients receiving intraoperative ventilation during extracorporeal life support will be excluded

NCT ID: NCT06287632 Not yet recruiting - Obesity, Abdominal Clinical Trials

CPAP in Patients With Severe Obesity After Anesthesia

Start date: June 2024
Phase: N/A
Study type: Interventional

The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1. Does a recruitment maneuver and CPAP set to intrathoracic pressure (ITP) improve cardiopulmonary function compared to standard CPAP settings in patients with severe obesity after anesthesia? 2. Does the location of adipose tissue influence the response to CPAP settings in patients with severe obesity after anesthesia? Participants will undergo monitoring of their intrathoracic pressure using an esophageal catheter. In the recovery area after anesthesia, participants will receive two CPAP settings, each for 20 minutes. - Intervention 1: Recruitment maneuver and CPAP will set to the level of intrathoracic pressure - Intervention 2: CPAP set to home settings (if OSA is present) or between 8-10 cmH20 (if OSA is not present).

NCT ID: NCT06157073 Not yet recruiting - ARDS Clinical Trials

Efficacy and Safety of Automated Closed-loop Ventilator vs Conventional Open-loop Ventilator in the Emergency Department

AVAC
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Patients presenting to the emergency department (ED) may require breathing support with machines depending on the condition. Throughout the breathing support, the settings on the breathing machines will be tailored to the patient's requirements. These settings are manually adjusted by trained physicians. Currently, there are machines which can automatically change the settings based on real-time specific information obtained from the patient. This study aims to compare the use of machines which require manual adjustments (open-loop conventional ventilators) and machines which can automatically change the settings (closed-loop automated ventilators). Patients will be carefully selected to ensure no harm is caused whilst delivering the best care. This study will look into the duration when patients are receiving optimum settings and levels of oxygen and carbon dioxide in the blood. The outcomes of this study would allow us to identify methods to improve patient care.

NCT ID: NCT05875883 Not yet recruiting - Ultrasound Clinical Trials

Phrenic Identification in the ICU

Start date: August 7, 2023
Phase:
Study type: Observational

This will be a prospective observational study where the investigator will scan patients' necks with an ultrasound and look for anatomical landmarks that may help identify the phrenic nerve.

NCT ID: NCT05726578 Not yet recruiting - Echocardiography Clinical Trials

Integrated Echocardiography and Chest Ultrasound Assessment of Lung Recruitment in Preterm Infants

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The primary aim of this work is to evaluate the role of high frequency oscillatory ventilation (HFOV) in recruitment of lung in preterm newborns 32 to 37 weeks gestational age with moderate to severe respiratory distress. The secondary aim is to evaluate the role of chest ultrasound in monitoring of lung recruitment in comparison to routine chest x ray in those babies. Also cardiac hemodynamics will be assesed using functional echocardiography.

NCT ID: NCT05490147 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Effect of Low Tidal Ventilation on Intraoperative Bleeding in Laparoscopic Major Hepatectomy

Start date: August 8, 2022
Phase: N/A
Study type: Interventional

This randomized controlled study's objective is to find a safer mechanical ventilation strategy to reduce intraoperative bleeding in liver cancer patients undergoing laparoscopic major liver resection. The hypothesis is that low tidal volume ventilation in laparoscopic major hepatectomy results in less bleeding.

NCT ID: NCT04229810 Not yet recruiting - Ventilator Lung Clinical Trials

Individualized Perioperative Open Lung Ventilatory Approach in Emergency Abdominal Laparotomy. A Prospective Multicenter Randomized Controlled Trial.

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

Prospective multicenter randomized controlled trial. Individualized perioperative open lung ventilatory approach in emergency abdominal laparotomy.

NCT ID: NCT03881033 Not yet recruiting - Ultrasound Clinical Trials

Determination of Optimal Mask Ventilation Mode in Pediatrics Using Real-time Ultrasonography

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The peak inspiratory pressure during face mask ventilation for general anesthesia is closely correlated with gastric insufflation. High pressure increases the amount of air in stomach and low pressure could decrease the tidal volume, therefore ideal pressure means the pressure guarantee adequate ventilation with minimal gastric insufflation. The aim of this study is finding the proper pressure and mode of face mask ventilation in pediatric patients.