Preterm Birth Clinical Trial
Official title:
The Effect on Physiological Variables of Prone and Supine Positions Given to Preterm Infants Receiving Mechanical Ventilation
Positioning, which is one of the individualized developmental care methods, is known as the important care support process which is applied with the purpose of ensuring the least damage from the environmental. Positioning in preterm infants is the basis of neonatal nursing care. Positioning in preterm infants receiving mechanical ventilation support is important in terms of physiological and neurodevelopment. In infants undergoing respiratory support in NICU, it is important to determine the appropriate position, the frequency and duration of position change in order to reduce the oxygen need. In this respect, the aim of this study, designed as a randomized controlled trial, was to determine the effect of supine and prone positions on physiological variables (oxygen saturation and heart rate) of preterm infants receiving mechanical ventilation.
In infants undergoing respiratory support in NICU, it is important to determine the
appropriate position, the frequency and duration of position change in order to reduce the
oxygen need. Therefore, the aim of this randomized controlled study, test the efficacy of two
different positions (prone-supine) given to preterm newborns receiving mechanical
ventilation.The study was conducted from February 2015 to June 2016.
Participants and setting:
We were interested in establishing the difference between the supine position and the prone
position, with an error margin of 10%. According to the formula of the calculated sample
size, for a crossover design with a = 0.05, the sample size required to achieve a 90% power
is 36 infants. Thirty-eight infants who met the inclusion criteria of the study were selected
and invited to participate. Of these, parents of 38 infants consented. A convenience sample
of hospitalized preterm infants (less than 37 weeks gestational age) was selected from a
tertiary neonatal intensive care unit of a teaching and research hospital in Turkey. Preterm
infants were divided into two groups by randomization according to position priority (n =
38). First group was first supine position followed by prone position (n = 19), second group
was first prone position, then supine position (n = 19). The priority of the positions to be
given to preterm infants was randomly determined using the closed envelope method. The
positions of infants were written in envelopes and closed. The clinical nurse, who was not in
the research, pulled the envelope and identified position group of the infant . Thus, data
were collected for both the prone and the supine position from a newborn.
Procedure and data collection:
The infants involved in the study were cared for in a incubator and wore diapers only. The
temperature of the incubator was set to maintain a body temperature ranging from 36.5 to 37.2
°C. After necessary routine procedures such as diapering, body cleaning, weighing and
suctioning were completed, each subject was randomly assigned to the supine-prone group or
prone-supine group sequence. All of the positions of preterm infants were given carefully by
the researcher.
Data Collection Tools:
Infant descriptive characteristics form: The form was developed in light of the relevant
literature to collect data about gender, age, gestational age, body weight at study.
Infant's clinical variables form. The form was developed by the researchers according to the
literature to collect data such as infant feeding method, caffeine and surfactant treatment.
Physiological variable monitoring form: The form was developed to record heart rate (HR)
(min) and oxygen saturation (% SpO2) values in the literature.
Pulse Oximeter Device: A pulse oximetry was used to determine HR and SpO2. The physiological
parameters were measured and recorded every 15 minute for a total of 120 minute. The normal
vital sign ranges assumed for the study subjects were as follows; heart rate range of 121 to
179 beats per minute, oxygen saturation range ≥92%. The pulse oximetry was calibrated as
recommended by the manufacturer prior to use at the beginning of each shift within the study
period. The pulse oximetry probe was attached to the foot of the leg.All of the measurements
were performed by researcher who carefully and prudently recorded the infants' response
throughout the study process.
Positioning material:
Rolled sheets were used when infants were given positions.
Statistical analysis:
Data were analyzed using SPSS version 22.0 (SPSS Inc., Chicago, IL, USA) statistical program.
Descriptive statistics were reported using frequencies, percentages, mean values, standard
deviation, and range. The Kolmogorov-Smirnov test was conducted to assess the distribution of
the variables in order to use a parametric or non-parametric test. All the variables were
normally distributed. Therefore, parametric tests such as analysis of variance and t-test
were used to determine the differences in variables between groups. Variance analysis was
used for repeated measurements of heart rates and oxygen saturation measured by infants at 15
min intervals. A value of p <0.05 was considered statistically significant.
Ethical considerations:
İn the study, written consent was obtained from the ethics committee, institutions and
families.
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