Ventilator Acquired Pneumonia Clinical Trial
Official title:
Rapid Bacterial Identification and Antibiotic Resistance Testing in Critically Ill Adults at Risk for Ventilator Acquired Pneumonia (VAP).
Verified date | December 2019 |
Source | Denver Health and Hospital Authority |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Critically ill patients on a breathing machine are at risk of developing a type of pneumonia called Ventilator Acquired Pneumonia (VAP). The purpose of this study is to determine if regular lung rinses sent for microbiological testing can reduce the time to diagnose VAP. The study also plans to test the accuracy and speed of a new technology, using multiplexed automated digital microscopy, to identify the germs causing the VAP.
Status | Completed |
Enrollment | 37 |
Est. completion date | September 19, 2019 |
Est. primary completion date | September 19, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: 1. Written, informed consent (by surrogate if unconscious or if altered mental status) 2. = 18 years old 3. Admission to a Medical Intensive care unit 4. Orally/nasally intubated, evaluable within 72 h of initial intubation 5. Expected to remain mechanically ventilated for at least 48 h after the first study procedure Exclusion Criteria: 1. Previously documented cystic fibrosis 2. Diffuse bronchiectasis 3. Severe or massive hemoptysis 4. Presence of an advanced directive to withhold life-sustaining treatment 5. Morbid state or expected to survive less than 14 days because of an advanced co-morbid medical condition 6. Participation in a clinical trial of any unlicensed drug or device within 30 days 7. Pregnant or Nursing |
Country | Name | City | State |
---|---|---|---|
United States | Denver Health Medical Center | Denver | Colorado |
Lead Sponsor | Collaborator |
---|---|
Denver Health and Hospital Authority | Accerl8 Technology Corporation, National Center for Research Resources (NCRR) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Reduction in time to diagnosis and treatment of VAP in an at risk population | 30 days |
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