Functional Residual Capacity (FRC) Guided Alveolar Recruitment Strategy

Status Completed

Clinical Trial Summary

In ventilated patients open endotracheal suctioning may lead to alveolar derecruitment, which can be monitored by means of functional residual capacity (FRC) measurements. The investigators hypothesized that a recruitment strategy based on FRC measurements would improve oxygenation and regional ventilation after an open endotracheal suctioning manoeuvre.

Clinical Trial Description

In mechanically ventilated patients the functional residual capacity will be measured before (baseline) and after an open endotracheal suctioning manoeuvre. Based on these changes patients will be divided into two groups: Group A with more than 94% of baseline FRC, and Group B with less than 94% of baseline FRC. Both groups will be randomized to receive an alveolar recruitment manoeuvre or no alveolar recruitment manoeuvre, leading to four groups. Oxygenation and regional ventilation with electrical impedance tomography will be studied. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00779090
Study type	Interventional
Source	University of Luebeck
Contact
Status	Completed
Phase	Phase 4
Start date	October 2007
Completion date	October 2008

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06063798` - Respiratory Effects of Flow-Controlled Ventilation and Jet Ventilation in Patients Undergoing Laryngotracheal Surgery	N/A
Completed	`NCT03657368` - Ventilation Strategy During General Anesthesia for Orthopedic Surgery	N/A
Completed	`NCT02943863` - Regional Ventilation During High Flow Nasal Cannula and Conventional Nasal Cannula in Patients With Hypoxia	N/A
Completed	`NCT01056939` - Neurally Adjusted Ventilatory Assist (NAVA) in Pediatric Patients	N/A
Completed	`NCT03287752` - BASKA Mask Versus Endo Tracheal Tube in Gynecological Laparoscopic Surgery
Completed	`NCT04014920` - Non-invasive Ventilation Following Extubation (Prophylactic) to Prevent Extubation Failure in Critically Obese Patients	N/A
Completed	`NCT04281589` - End-tidal Carbon Dioxide Monitoring in Low Tidal Volume Ventilation	N/A
Completed	`NCT02751047` - Manual Ventilation Versus Pressure Controlled Mechanical Ventilation in Children	N/A
Completed	`NCT03139448` - Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy	N/A
Recruiting	`NCT05823688` - Electrical Impedance Tomography (EIT) Monitoring of Regional Ventilation During Pediatric Laparoscopy
Recruiting	`NCT03106974` - A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Obese Patients	N/A
Completed	`NCT03996161` - Effect of Semi-sitting Position on Mask Ventilation	N/A
Completed	`NCT03083379` - Pilot Evaluation Comparing Regional Distribution of Ventilation During Lung Expansion Therapy	N/A
Completed	`NCT00500916` - Different Techniques for Insertion of the ProSeal Laryngeal Mask Airway in Patients With Difficult Airway	N/A
Completed	`NCT05523752` - Insertion of Different Supraglottic Airway Devices on Manikin	N/A
Completed	`NCT00919971` - Bispectral Index (BIS) on Ventilated Patients in the Prehospital Setting	N/A
Completed	`NCT05388266` - Effect of Paratracheal Pressure on Mask Ventilation	N/A
Completed	`NCT03368352` - Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.	Early Phase 1
Completed	`NCT01168557` - Stress Echo and Electric Impedance Tomography (EIT) Pilot Study	N/A
Completed	`NCT01053455` - Observational Crossover Study Comparing Oxygenation and Ventilation Using SiPAP Versus CPAP in LBW Infants	N/A