Ventilation Perfusion Mismatch Clinical Trial
Official title:
Effect of Patient Position on Arterial, End-tidal and Transcutaneous Carbon Dioxide Partial Pressure in Patients Undergoing Laparoscopic Surgery
Investigators evaluate the effect of patient position (Trendelenburg and reverse Trendelenburg) on arterial, end-tidal and transcutaneous carbon dioxide partial pressure in patients undergoing laparoscopic surgery.
Status | Not yet recruiting |
Enrollment | 142 |
Est. completion date | April 2019 |
Est. primary completion date | April 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years and older |
Eligibility |
Inclusion Criteria: - adult patients undergoing laparoscopic surgery (expected duration of pneumoperitoneum > 1 hour) in the Trendelenburg or reverse Trendelenburg positions Exclusion Criteria: - hemodynamically unstable patients due to decompensated heart failure, sepsis, or symptomatic arrhythmia, etc. - symptomatic pulmonary disease, chronic obstructive pulmonary disease |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
SMG-SNU Boramae Medical Center |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Difference between arterial and end-tidal carbon dioxide pressures | Difference between arterial and end-tidal carbon dioxide partial pressures are calculated. (Arterial carbon dioxide partial pressure minus end-tidal carbon dioxide partial pressure) | baseline before CO2 pneumoperitoneum, every 30 minute during CO2 pneumoperitoneum, and 15 min after deflation of CO2 | |
Secondary | Agreement among arterial, end-tidal, and transcutaneous carbon dioxide partial pressure | Arterial, end-tidal, and transcutaneous carbon dioxide partial pressures are recorded and the agreement among the values is analyzed using the statistical test. | baseline before CO2 pneumoperitoneum, every 30 minute during CO2 pneumoperitoneum, and 15 min after deflation of CO2 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05535543 -
Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress Syndrome
|
||
Withdrawn |
NCT04508933 -
Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients
|
||
Completed |
NCT04818164 -
Prone Position Improves End-Expiratory Lung Volumes in COVID-19 Acute Respiratory Distress Syndrome
|
||
Recruiting |
NCT05801224 -
Vascular ARDS Recruitment After Inhaled Nitric Oxide
|
N/A | |
Recruiting |
NCT06246838 -
68Ga PET/CT Versus 99mTc SPECT/CT for Lung Perfusion and Ventilation Scintigraphy; a Technical and Practical Feasibility Study
|
N/A | |
Recruiting |
NCT06181539 -
Evaluate the Effect of Prone Ventilation on Ventilated-blood Flow Ratio in Patients With ARDS by EIT
|
||
Suspended |
NCT04249414 -
Post-hoc Analysis of Regional Pulmonary Perfusion and Hemodynamic Parameters Measured by Electrical Impedance Tomography
|
||
Completed |
NCT05341258 -
Arterial and End-Tidal CO2 Gradient as a Mortality Predictor in Critical Care Patients
|
N/A | |
Recruiting |
NCT04511923 -
Nebulised Heparin to Reduce COVID-19 Induced Acute Lung Injury
|
Phase 1/Phase 2 | |
Completed |
NCT01943227 -
Effect of Alveolar Minute Ventilation on Respiratory Gas Heat Content
|