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Venous Thromboembolism clinical trials

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NCT ID: NCT02877251 Not yet recruiting - Pulmonary Embolism Clinical Trials

Mexican Multidisciplinary Registry of Patients With Venous Thromboembolic Disease

REMMITE
Start date: December 2023
Phase:
Study type: Observational [Patient Registry]

REMMITE, a retrospective and prospective registry with one-year follow-up, will provide valuable insights into the clinical diagnosis, management, treatment trends as well as related outcomes of three cohorts: DVT, DVT-PE, PE patients throughout many regions of Mexico and through different health care systems.

NCT ID: NCT02761044 Not yet recruiting - Clinical trials for Venous Thromboembolism

Rivaroxaban vs Apixaban on Menstrual Blood Loss

RAMBLE
Start date: May 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate women with heavy menstrual bleeding that have venous thromboembolism or atrial fibrillation. There will be a comparison of the anti-coagulants; drugs rivaroxaban or apixaban to see if one of the drugs works better to control bleeding during the women's menses.

NCT ID: NCT02503904 Not yet recruiting - Clinical trials for Venous Thromboembolism

Tumescent Antibiotic Delivery for Prevention of Surgical Site Infection

Start date: October 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The principal aim of the present research is to compare two methods of antibiotic delivery: concomitant tumescent antibiotic delivery (TAD) and intravenous antibiotic delivery (IVAD) versus IVAD alone, (TAD+IVAD vs IVAD), with respect to the prevention of surgical site infections (SSI). The investigators hypothesize that TAD+IVAD will significantly reduce the incidence of SSI compared to IVAD. TAD is the subcutaneous infiltration of a dilute solution of antibiotic(s) in a solution of tumescent local anesthesia (TLA). TLA consists of a dilute solution of lidocaine (1gm/L), epinephrine (1mg/L) and sodium bicarbonate (10mEq/L) in 0.9% physiologic saline. A secondary aim of this study is to compare TAD+IVAD vs IVAD with respect to the prevention of post-operative venous thromboembolism (VTE).

NCT ID: NCT02420626 Not yet recruiting - Pulmonary Embolism Clinical Trials

Evaluation of the Short and Long Term Performance and Clinical Outcomes of the Crux Vena Cava Filter System

Start date: January 2016
Phase: N/A
Study type: Observational

The Crux Vena Cava Filter (VCF) Registry is a clinical study, sponsored by Volcano Corporation, to evaluate the short and long term performance and clinical outcomes of the Crux Vena Cava Filter System.

NCT ID: NCT02160964 Not yet recruiting - Pulmonary Embolism, Clinical Trials

Using a Novel Algorithm to Improve the Retrieval Rate of Inferior Vena Cava Filters (iRetrieve Study)

iRetrieve
Start date: May 2015
Phase: N/A
Study type: Observational

Since 2003, that the first retrievable IVC filter was introduced in the U.S,improvements have been made in the filter design to resolve problems of structural integrity and increase the ability to remove the filter after longer periods of time.The FDA issued a communication in August 2010 advising physicians to remove retrievable filters whenever possible and updated that letter again in May 2014 due to concerns that these retrievable IVC filters, intended for short-term placement, are not always removed once a patient's risk for PE subsides. Known long term risks associated with IVC filters include but are not limited to lower limb deep vein thrombosis (DVT), filter fracture, filter migration, filter embolization and IVC perforation.

NCT ID: NCT01357941 Not yet recruiting - Pulmonary Embolism Clinical Trials

Need for Antepartum Thromboprophylaxis in Pregnant Women With One Prior Episode of Venous Thromboembolism (VTE)

ROCITP2
Start date: September 2011
Phase: N/A
Study type: Observational

Pregnant women with a prior history of venous thromboembolism (VTE) are at increased risk of recurrent VTE. Current guidelines assessing the role of prophylaxis in pregnant women with prior VTE are based primarily on expert opinion and the optimal clinical management strategy remains unclear. This multicentre, prospective cohort study aims to test the following hypotheses: 1. Antepartum prophylaxis with fixed-dose low molecular-weight heparin (LMWH) is safe, convenient and associated with an acceptably low risk of recurrent VTE in women with a single prior episode of VTE that was either unprovoked or associated with a minor transient risk factor. (Moderate risk cohort) 2. Withholding antepartum prophylaxis is safe (recurrence risk <1%) in pregnant women with a single prior episode of VTE provoked by a major transient risk factor. (Low risk cohort) All study patients will receive 6 weeks of postpartum prophylaxis.