Vasospastic Angina Clinical Trial
Official title:
Diagnostic Usefulness of Multidetector Coronary CT in Vasospastic Angina
The purpose of this study is to compare the extent of coronary vessel stenosis between coronary spasm-induced angina attacks (named vasospastic angina, VSA) patients and health volunteers by multi-detector computed tomography angiography (MDCTA), and to evaluate the diagnostic efficacy of MDCTA in patients with VSA.
Vasospastic angina (VSA) was characterized by transient ischemic ST-segment change during
angina attacks. Coronary spasm provocation test, as a diagnostic golden standard, has been
widely used for the management of VSA according to JCS 2013 guidelines.
With regard to the characteristics of spasm segment, had been clearly described by other
invasive imaging methods including intravascular ultrasound and optical coherence tomography.
However, there is potential risk during these invasive procedures, such as severe myocardial
ischemia or fatal arrhythmia.
Presently available imaging test for coronary artery disease including multi-detector
computed tomography angiography (MDCTA) with high diagnostic accuracy to evaluate coronary
artery stenosis. However, the diagnostic accuracy of MDCTA in patients with VSA is lacking.
Therefore, more efficient and safe noninvasive diagnostic method is required for the
detection of angina-like attacks patients.
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