Vasospastic Angina Clinical Trial
Official title:
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of Pletaal(Cilostazol) in Subjects With Vasospastic Angina
This study will be conducted in accordance with the local regulation of New Drug
Application. Overall duration of this trial will be 3 years after approval of KFDA.
Each subject will participate around 7 weeks, which include the 2 weeks Amlodipine run-in
period, 4 weeks double blind period and 1 week safety follow up period
A Multicenter, Randomized, Double-Blind, Placebo-controlled, Parallel group, Therapeutic
confirmatory Study.
The subject who has at least one episode of chest pain weekly and at least two episodes of
chest pain during last week despite Amlodipine 5mg qd taking during 2 weeks will have
treatment of Pletaal(Cilostazol) or Placebo for 4 weeks. Pletaal(Cilostazol) is taken 100mg
oral tablets bid during 2 weeks after dosing of Pletaal(Cilostazol) 50mg oral tablets bid
during 2 weeks. Placebo of Pletaal(Cilostazol) is used as the control medication.
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