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Clinical Trial Summary

To investigate whether patients with cerebral vasospasm associated with aneurysmal subarachnoid hemorrhage have a better prognosis with intrathecal nicardipine injection via extraventricular drainage or lumbar drainage.


Clinical Trial Description

Objective: To investigate whether patients with cerebral vasospasm associated with aneurysmal subarachnoid hemorrhage have a better prognosis with intrathecal nicardipine injection via extraventricular drainage or lumbar drainage. Design: This study is a multi-center, prospective, double-blinded, randomized controlled trial. Interventions: First, 6 ml of cerebrospinal fluid is withdrawn from the EVD or LD catheter, and then 4 ml of nicardipine hydrochloride is injected into the EVD or LD drain tube, followed by 2 ml of 0.9 % sodium chloride solution (NaCl), and then the EVD or LD tube was clamped for 2 hours after the injection was completed, then kept open as clinically necessary until the next dose (twice a day). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06329635
Study type Interventional
Source The Affiliated Hospital Of Guizhou Medical University
Contact Guangtang Chen, MD
Phone +8618286089635
Email 18286089635@163.com
Status Recruiting
Phase N/A
Start date May 27, 2024
Completion date May 2026

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