Vasculitis Clinical Trial
Official title:
Longitudinal Study for Relapsing Polychondritis
NCT number | NCT04919538 |
Other study ID # | VCRC5508 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | February 26, 2021 |
Est. completion date | January 2026 |
Relapsing polychondritis (RP) is a rare systemic inflammatory disease characterized by recurrent inflammation of cartilage including ears, nose, tracheobronchial tree, chest wall and joints. Less commonly, it can cause inflammation of eyes, vasculature, nervous system, skin and inner ear. The purpose of this study is to study the pathogenesis of RP.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | January 2026 |
Est. primary completion date | January 2026 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - 1. Any subject considered to have a diagnosis of relapsing polychondritis according to the investigator. Exclusion Criteria: - 1. Inability to provide consent, or in the case of minors, assent. |
Country | Name | City | State |
---|---|---|---|
United States | University of Pennsylvania | Philadelphia | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
University of Pennsylvania |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Evaluate the pathogenesis of relapsing polychondritis using disease history. | To study the manner of development of disease in patients affected with relapsing polychondritis. | Study completion; from baseline through month 36. | |
Secondary | PROMIS Questionnaires | Questions will ask about fatigue on the PROMIS short form. | Baseline, month 6, month 12, month 18, month 24, month 30, month 36 | |
Secondary | PROMIS Questionnaires | Questions will ask about pain interference on the PROMIS short form. | Baseline, month 6, month 12, month 18, month 24, month 30, month 36 | |
Secondary | PROMIS Questionnaires | Questions will ask about physical function on the PROMIS short form. | Baseline, month 6, month 12, month 18, month 24, month 30, month 36 | |
Secondary | PROMIS Questionnaires | Questions will ask about global health on the PROMIS short form. | Baseline, month 6, month 12, month 18, month 24, month 30, month 36 |
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