Vascular Stiffness Clinical Trial
— CardioBreathOfficial title:
Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity On Normotensive Postmenopause Women : Randomized Clinical Trial
Existing data points to relevant beneficial effects of respiratory exercises on cardiovascular health, with special regards to decreases on arterial pressure and improves on autonomic and vascular profiles, though mechanistics of such results have not yet been cleared. Among the available ways to perform respiratory exercises, there is the highly recommended Inspiratory Muscle Training (IMT) and slow breathing exercises like Yoga pranayamas. Lately, the development of new technologies has allowed the use of Apps to perform respiratory exercises. This study will be take the just developed CardioBreath®App to validate it as a tool to perform respiratory exercises. Therefore, it will be compared to IMT on cardiac vagal modulation and pulse wave velocity on normotensive post menopause women.
Status | Recruiting |
Enrollment | 24 |
Est. completion date | July 30, 2025 |
Est. primary completion date | November 30, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 45 Years to 65 Years |
Eligibility | Inclusion Criteria: - Follicle Stimulating Hormone (FSH)>35mui/ml - minimum 12 months amenorrhea - sedentary life style (less than 150 minutes per week of exercise) Exclusion Criteria: - Hypertension - Diabetes - Obesity - Use of Betablockers - recent cardiovascular events or surgery - renal alterations - respiratory and/or motor pathologies - smoking - BMI>29,9 |
Country | Name | City | State |
---|---|---|---|
Brazil | Instituto de Cardiologia do Rio Grande do Sul | Porto Alegre | Rio Grande Do Sul |
Lead Sponsor | Collaborator |
---|---|
Instituto de Cardiologia do Rio Grande do Sul |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Respiratory rate by Pneumotrace respiratory belt | Respiratory rate in cycles per minute (CPM) | 30 minutes along with Finometer | |
Other | Diaphragm Thickness by ultrasound | Increase diaphragm thickness (mm) | 5 minutes | |
Primary | Cardiovascular autonomic control by heart rate variability(HRV) | High Frequency (HF) component of HRV (ms2 = squared milliseconds) as measure of vagal modulation | 30 minutes | |
Secondary | Carotid -femoral pulse wave velocity (Complior) | Reduction of carotid -femoral pulse wave velocity (m/s) | 10 minutes |
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