The Effects of Types of Fruits and Vegetables on Vascular Function — CIRCUS  

Blood Pressure Clinical Trial

Official title: The Effects of Types of Fruits and Vegetables on Vascular Function in Prehypertensive Participants: a Pilot Study

Status Completed

Clinical Trial Summary

The CIRCUS study is a randomised controlled, cross-over trial to evaluate the effects of increased intakes of citrus fruits and cruciferous vegetables on vascular function in 36 untreated, prehypertensive participants.

Clinical Trial Description

The study comprises three 14-day dietary intervention periods, preceded by one week run-in period and separated by one week wash-out periods, 9 weeks in total. The diet will be fully controlled and provided by the researchers. Participants will receive in random order three interventions:

• 1 portion of fruits plus 1 portion of vegetables, of commonly consumed types per day. Intakes are at 25th percentile of UK consumption and will exclude citrus fruits, cruciferous and allium vegetables.

• 4 portions of fruits plus 4 portions of vegetables, of commonly consumed types per day excluding citrus fruits, cruciferous and allium vegetables.

• 4 portions of citrus fruits plus 4 portions of cruciferous vegetables per day. ;

Related Conditions & MeSH terms

• Blood Pressure
• Cardiovascular Risk Factor
• Vascular Stiffness

• NCT number: NCT03410342
• Study type: Interventional
• Source: University of Cambridge
• Status: Completed
• Phase: N/A
• Start date: September 4, 2017
• Completion date: June 21, 2021